Ch\u1ea9n \u0111o\u00e1n th\u1ef1c t\u1ebf c\u1ee7a b\u1ec7nh s\u00e0i s\u1ed1t \u1edf ch\u00f3 ch\u1ee7 y\u1ebfu d\u1ef1a v\u00e0o nghi ng\u1edd l\u00e2m s\u00e0ng. H\u1ea7u h\u1ebft ch\u00f3 v\u1edbi b\u1ec7nh n\u1eb7ng n\u1ec1 c\u00f3 c\u00e1c bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng \u0111\u1ee7 r\u00f5 r\u1ec7t \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n c\u00f3 c\u01a1 s\u1edf, nh\u01b0ng c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean c\u1ee7a nh\u1eefng ch\u00f3 gi\u00e0 h\u01a1n th\u01b0\u1eddng b\u1ecb ch\u1ea9n \u0111o\u00e1n kh\u00f4ng ch\u00ednh x\u00e1c l\u00e0 vi\u00eam kh\u00ed \u2013 ph\u1ebf qu\u1ea3n truy\u1ec1n nhi\u1ec5m.<\/p>\n
Ch\u1ea9n \u0111o\u00e1n th\u1ef1c t\u1ebf c\u1ee7a s\u00e0i s\u1ed1t c\u1ee7a ch\u00f3 ch\u1ee7 y\u1ebfu d\u1ef1a v\u00e0o nghi ng\u1edd l\u00e2m s\u00e0ng. H\u1ea7u h\u1ebft ch\u00f3 v\u1edbi b\u1ec7nh n\u1eb7ng n\u1ec1 c\u00f3 c\u00e1c bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng \u0111\u1ee7 r\u00f5 r\u1ec7t \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n c\u00f3 c\u01a1 s\u1edf, nh\u01b0ng c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean c\u1ee7a nh\u1eefng ch\u00f3 gi\u00e0 h\u01a1n th\u01b0\u1eddng b\u1ecb ch\u1ea9n \u0111o\u00e1n kh\u00f4ng ch\u00ednh x\u00e1c l\u00e0 vi\u00eam kh\u00ed \u2013 ph\u1ebf qu\u1ea3n truy\u1ec1n nhi\u1ec5m. Ngo\u00e0i ra, m\u1ed9t l\u1ecbch s\u1eed \u0111\u1eb7c tr\u01b0ng c\u1ee7a ch\u00f3 con kh\u00f4ng ti\u00eam ph\u00f2ng 3 \u0111\u1ebfn 6 th\u00e1ng tu\u1ed5i l\u00e0 m\u1ed9t nghi ng\u1edd ch\u1ea9n \u0111o\u00e1n.<\/p>\n
Ch\u00f3 v\u1edbi b\u1ec7nh truy\u1ec1n nhi\u1ec5m \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean n\u00ean \u0111\u01b0\u1ee3c gi\u1eef trong m\u00f4i tr\u01b0\u1eddng m\u00e0 s\u1ea1ch s\u1ebd, \u1ea5m \u00e1p. Ngo\u00e0i ra, l\u00e0m s\u1ea1ch n\u01b0\u1edbc m\u1eaft \u2013 m\u0169i v\u00e0 ph\u00f2ng ng\u1eeba ph\u1ee5 nhi\u1ec5m vi khu\u1ea9n (th\u01b0\u1eddng v\u1edbi Bordetella bronchiseptica) v\u1edbi li\u1ec7u tr\u00ecnh kh\u00e1ng khu\u1ea9n ph\u1ed5 r\u1ed9ng v\u00e0 thu\u1ed1c long \u0111\u1eddm ho\u1eb7c kh\u00ed dung h\u00f3a. L\u1ef1a ch\u1ecdn kh\u00e1ng vi khu\u1ea9n \u0111\u1ea7u ti\u00ean t\u1ed1t cho vi\u00eam ph\u1ed5i \u2013 ph\u1ebf qu\u1ea3n bao g\u1ed3m ampicillin, tetracycline, v\u00e0 chloramphenicol.<\/p>\n
Ng\u01b0ng \u0103n, u\u1ed1ng v\u00e0 thu\u1ed1c c\u1ea5p \u0111\u01b0\u1eddng mi\u1ec7ng n\u1ebfu th\u00fa b\u1ecb \u00f3i m\u1eeda v\u00e0 ti\u00eau ch\u1ea3y. Ti\u00eam thu\u1ed1c ch\u1ed1ng n\u00f4n v\u00e0 b\u1ed5 sung dung d\u1ecbch \u0111i\u1ec7n gi\u1ea3i, nh\u01b0 lactated Ringer n\u00ean \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch hay d\u01b0\u1edbi da, ph\u1ee5 thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng m\u1ea5t n\u01b0\u1edbc c\u1ee7a ch\u00f3 b\u1ec7nh.<\/p>\n
\u0110i\u1ec1u tr\u1ecb cho r\u1ed1i lo\u1ea1n th\u1ea7n kinh b\u1eb1ng dexamethasone (2,2 mg\/kg, ti\u00eam m\u1ea1ch m\u00e1u [IV]); Ki\u1ec3m so\u00e1t co gi\u1eadt \u0111\u01b0\u1ee3c t\u1ed1t nh\u1ea5t v\u1edbi diazepam ti\u00eam t\u0129nh m\u1ea1ch (parenteral diazepam; 0,5 \u0111\u1ebfn 2 mg\/kg, \u0111\u1eb7t tr\u1ef1c tr\u00e0ng hay ti\u00eam t\u0129nh m\u1ea1ch ch\u1eadm).<\/p>\n
Mi\u1ec5n d\u1ecbch m\u1eb9 truy\u1ec1n kh\u00e1ng CDV gi\u1ea3m c\u00f2n m\u1ed9t n\u1eeda trong th\u1eddi gian 8,4 ng\u00e0y. C\u00f3 3% kh\u00e1ng th\u1ec3 truy\u1ec1n sang ch\u00f3 con t\u1eeb t\u1eed cung, v\u00e0 97% truy\u1ec1n qua s\u1eefa \u0111\u1ea7u, d\u1eabn \u0111\u1ebfn c\u00f3 \u0111\u01b0\u1ee3c hi\u1ec7u gi\u00e1 kh\u00e1ng th\u1ec3 ban \u0111\u1ea7u trong ch\u00f3 con s\u01a1 sinh, m\u00e0 h\u00e0m l\u01b0\u1ee3ng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 77% so v\u1edbi \u1edf ch\u00f3 m\u1eb9. Ch\u00f3 con kh\u00f4ng nh\u1eadn \u0111\u1ee7 s\u1eefa \u0111\u1ea7u ch\u1ec9 c\u00f3 \u0111\u01b0\u1ee3c b\u1ea3o h\u1ed9 t\u1eeb 1 \u0111\u1ebfn 4 tu\u1ea7n. Kh\u00e1ng th\u1ec3 m\u1eb9 truy\u1ec1n th\u01b0\u1eddng m\u1ea5t \u0111i l\u00fac kho\u1ea3ng 12 \u0111\u1ebfn 14 tu\u1ea7n tu\u1ed5i. C\u1ea5p vaccin cho ch\u00f3 con tu\u1ea7n, kho\u1ea3ng 6 \u0111\u1ebfn 16 tu\u1ea7n, sau khi ch\u00f3 con \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c s\u1eefa \u0111\u1ea7u, c\u00e1ch nhau 3 \u0111\u1ebfn 4 tu\u1ea7n.<\/p>\n
Mi\u1ec5n d\u1ecbch sau khi kh\u1ecfi b\u1ec7nh nhi\u1ec5m t\u1ef1 nhi\u00ean hay sau khi ti\u00eam vaccin nh\u1eafc l\u1ea1i c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i \u0111\u1ebfn h\u00e0ng n\u0103m. Ch\u00f3 \u0111\u00e3 ti\u00eam vaccin t\u1eeb l\u00e2u c\u00f3 th\u1ec3 v\u1eabn ph\u00e1t b\u1ec7nh, khuy\u00ean ti\u00eam ph\u00f2ng nh\u1eafc l\u1ea1i, d\u00f9 cho \u0111\u00e3 c\u00f3 mi\u1ec5n d\u1ecbch k\u00e9o d\u00e0i b\u1edfi vaccin. Mi\u1ec5n d\u1ecbch \u0111\u1ed1i v\u1edbi b\u1ec7nh s\u00e0i s\u1ed1t ch\u00f3 sau khi ti\u00eam ph\u00f2ng nh\u1eafc l\u1ea1i \u0111\u01b0\u1ee3c bi\u1ebft l\u00e0 k\u00e9o d\u00e0i \u0111\u1ebfn 7 n\u0103m.<\/p>\n
S\u1eed d\u1ee5ng vaccin ch\u1ee9a virus nh\u01b0\u1ee3c \u0111\u1ed9c cho b\u1ea3o h\u1ed9 \u1edf ch\u00f3 tr\u01b0\u1edbc kia ch\u01b0a t\u1eebng ti\u00eam vaccin, khi ti\u00eam truy\u1ec1n vaccin n\u00e0y v\u00e0o m\u1ea1ch m\u00e1u \u00edt nh\u1ea5t 2 ng\u00e0y tr\u01b0\u1edbc khi c\u00f3 ph\u01a1i nhi\u1ec5m v\u1edbi CDV c\u00f3 \u0111\u1ed9c l\u1ef1c, n\u1ebfu ti\u00eam vaccin n\u00e0y d\u01b0\u1edbi da th\u00ec c\u1ea7n ph\u1ea3i ti\u00eam tr\u01b0\u1edbc \u00edt nh\u1ea5t 5 ng\u00e0y. Vi\u1ec7c ti\u00eam m\u1ea1ch m\u00e1u hay ti\u00eam b\u1eafp th\u1ecbt s\u1ebd ch\u1ec9 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng \u0111\u1ec3 t\u1ea1o b\u1ea3o h\u1ed9 cho ch\u00f3 \u0111\u00e3 b\u1ecb ph\u01a1i nhi\u1ec5m, ch\u01b0a \u0111\u01b0\u1ee3c ti\u00eam vaccin. Vi\u1ec7c ti\u00eam vaccin v\u00e0o m\u1ea1ch m\u00e1u t\u1ea1o b\u1ea3o h\u1ed9 nhanh ch\u00f3ng \u0111\u1ed1i v\u1edbi b\u1ec7nh s\u00e0i s\u1ed1t, t\u00f9y thu\u1ed9c v\u00e0o c\u00e1c c\u01a1 ch\u1ebf c\u1ee7a mi\u1ec5n d\u1ecbch c\u1ea3m nhi\u1ec5m, IFN hay mi\u1ec5n d\u1ecbch qua trung gian t\u1ebf b\u00e0o.<\/p>\n
C\u00e1c vaccin MLV d\u00f2ng Rockborn cho b\u1ea3o h\u1ed9 cao nh\u1ea5t v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y b\u1ec7nh l\u00e2m s\u00e0ng do vaccin nhi\u1ec1u nh\u1ea5t. Tuy nhi\u00ean, sau khi ti\u00eam vaccin v\u00e0 sau \u0111\u00f3 th\u1eed th\u00e1ch b\u1eb1ng virus c\u00f3 \u0111\u1ed9c l\u1ef1c, th\u00ec ch\u00f3 c\u00f3 \u0111\u01b0\u1ee3c \u201cmi\u1ec5n d\u1ecbch tinh khi\u1ebft \u2013 sterile immunity\u201d, c\u00f3 \u0111\u1eb7c \u0111i\u1ec3m l\u00e0 kh\u00f4ng c\u00f3 nh\u00e2n sao c\u1ee7a virus hay kh\u00f4ng thay \u0111\u1ed5i hi\u1ec7u gi\u00e1 kh\u00e1ng th\u1ec3 \u0111\u00e3 c\u00f3. Ng\u01b0\u1ee3c l\u1ea1i, c\u00e1c d\u00f2ng v\u00e0 c\u00e1c ch\u1ee7ng CDV kh\u00e1c c\u1ee7a vaccin th\u01b0\u1eddng \u00edt c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y b\u1ec7nh l\u00e2m s\u00e0ng do vaccin.<\/p>\n
Tuy nhi\u00ean, khi nh\u1eefng con ch\u00f3 \u0111\u00e3 ti\u00eam vaccin \u0111\u01b0\u1ee3c \u0111em th\u1eed th\u00e1ch, ch\u00fang c\u00f3 th\u1ec3 b\u1ecb nhi\u1ec5m b\u1edfi c\u00e1c virus c\u00f3 \u0111\u1ed9c l\u1ef1c, l\u00e0 ch\u1ec9 th\u1ecb cho th\u1ea5y b\u1ea3o h\u1ed9 k\u00e9m \u0111\u1ea7y \u0111\u1ee7 \u0111\u1ed1i v\u1edbi b\u1ec7nh l\u00e2m s\u00e0ng, s\u1ef1 gia t\u0103ng c\u00e1c hi\u1ec7u gi\u00e1 kh\u00e1ng th\u1ec3 c\u0169ng cho th\u1ea5y mi\u1ec5n d\u1ecbch n\u00e0y l\u00e0 \u201ckh\u00f4ng tinh khi\u1ebft \u2013 nonsterile\u201d. C\u00e1c nghi\u00ean c\u1ee9u th\u1eed th\u00e1ch v\u1edbi m\u1ed9t s\u1ed1 vaccin Onderstepoort cho th\u1ea5y t\u1ea1o \u0111\u01b0\u1ee3c b\u1ea3o h\u1ed9 k\u00e9o d\u00e0i 3 n\u0103m \u0111\u1ed1i v\u1edbi b\u1ec7nh l\u00e2m s\u00e0ng.<\/p>\n
Virus s\u00e0i s\u1ed1t \u1edf ch\u00f3 th\u00ec v\u00f4 c\u00f9ng nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c ch\u1ea5t s\u00e1t tr\u00f9ng th\u00f4ng th\u01b0\u1eddng. Th\u00fa b\u1ecb nhi\u1ec5m l\u00e0 ngu\u1ed3n virus ch\u1ee7 y\u1ebfu, do v\u1eady ch\u00fang ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e1ch ly kh\u1ecfi nh\u1eefng con ch\u00f3 kh\u1ecfe m\u1ea1nh kh\u00e1c. Ch\u00f3 th\u01b0\u1eddng b\u00e0i th\u1ea3i virus trong s\u1ef1 b\u00e0i ti\u1ebft cho 1 \u0111\u1ebfn 2 tu\u1ea7n sau khi b\u1ec7nh to\u00e0n th\u00e2n c\u1ea5p t\u00ednh. Nh\u1eefng h\u1ed3i ph\u1ee5c \u0111\u00f3 t\u1eeb b\u1ec7nh to\u00e0n th\u00e2n ho\u1eb7c h\u1ed3i ph\u1ee5c \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n sau bi\u1ec3u hi\u1ec7n th\u1ea7n kinh (kh\u00f4ng c\u00f3 b\u1ec7nh to\u00e0n th\u00e2n) c\u00f3 th\u1ec3 v\u1eabn b\u00e0i ti\u1ebft virus.<\/p>\n<\/p>\n
<\/p>\n
Ch\u1ea9n \u0111o\u00e1n th\u1ef1c t\u1ebf c\u1ee7a b\u1ec7nh s\u00e0i s\u1ed1t \u1edf ch\u00f3 ch\u1ee7 y\u1ebfu d\u1ef1a v\u00e0o nghi ng\u1edd l\u00e2m s\u00e0ng. H\u1ea7u h\u1ebft ch\u00f3 v\u1edbi b\u1ec7nh n\u1eb7ng n\u1ec1 c\u00f3 c\u00e1c bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng \u0111\u1ee7 r\u00f5 r\u1ec7t \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n c\u00f3 c\u01a1 s\u1edf, nh\u01b0ng c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean c\u1ee7a nh\u1eefng ch\u00f3 gi\u00e0 h\u01a1n th\u01b0\u1eddng […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1074","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/1074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/comments?post=1074"}],"version-history":[{"count":0,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/1074\/revisions"}],"wp:attachment":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/media?parent=1074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/categories?post=1074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/tags?post=1074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}