{"id":2301,"date":"2018-11-19T14:28:12","date_gmt":"2018-11-19T14:28:12","guid":{"rendered":"https:\/\/robot.yeupet.vn\/toxoplasmosis-tren-meo-va-cho\/"},"modified":"2018-11-19T14:28:12","modified_gmt":"2018-11-19T14:28:12","slug":"toxoplasmosis-tren-meo-va-cho","status":"publish","type":"post","link":"https:\/\/robot.yeupet.vn\/index.php\/2018\/11\/19\/toxoplasmosis-tren-meo-va-cho\/","title":{"rendered":"Toxoplasmosis Tr\u00ean M\u00e8o V\u00e0 Ch\u00f3"},"content":{"rendered":"

1. Nguy\u00ean nh\u00e2n<\/strong><\/p>\n

Toxoplasma gondii l\u00e0 m\u1ed9t sinh v\u1eadt \u0111\u01a1n b\u00e0o s\u1ed1ng k\u00fd sinh n\u1ed9i b\u00e0o b\u1eaft bu\u1ed9c, l\u00e2y nhi\u1ec5m t\u1ea5t c\u1ea3 c\u00e1c \u0110V m\u00e1u n\u00f3ng k\u1ec3 c\u1ea3 con ng\u01b0\u1eddi. M\u00e8o v\u00e0 th\u00fa h\u1ecd m\u00e8o l\u00e0 v\u1eadt ch\u1ee7 ch\u00ednh b\u00e0i ti\u1ebft oocyst nang k\u00e9n. T\u1ea5t c\u1ea3 c\u00e1c k\u00fd ch\u1ee7 kh\u00f4ng thu\u1ed9c h\u1ecd m\u00e8o l\u00e0 v\u1eadt ch\u1ee7 trung gian \u0111\u1ecbnh v\u1ecb \u1edf nang m\u00f4 (tissue cyst). C\u00f3 ba giai \u0111o\u1ea1n l\u00e2y nhi\u1ec5m trong b\u1ec7nh do Toxoplasma gondii bao g\u1ed3m: thoi tr\u00f9ng (sporozoite), tachyzoites v\u00e0 bradyzoites. Trong \u0111\u00f3, giai \u0111o\u1ea1n sporozoite \u1edf trong ph\u00e2n m\u00e8o v\u00e0 m\u00f4i tr\u01b0\u1eddng c\u00f3 hai h\u00ecnh th\u1ee9c b\u00e0o t\u1eed (sporulated oocyst) v\u00e0 kh\u00f4ng b\u00e0o t\u1eed (unsporulated oocyst). Giai \u0111o\u1ea1n \u1edf trong m\u00f4 c\u01a1 th\u1ec3 ch\u00fang \u1edf d\u1ea1ng tachyzoites v\u00e0 bradyzoites.<\/span><\/p>\n

\"Toxoplasmosis-tren-cho-va-meo\"<\/p>\n

T. gondii tachyzoites<\/p>\n

2. D\u1ecbch t\u1ec5 h\u1ecdc<\/strong><\/p>\n

T. gondii g\u00e2y b\u1ec7nh tr\u00ean m\u1ecdi l\u1ee9a tu\u1ed5i ch\u00f3 m\u00e8o. Tuy nhi\u00ean, m\u00e8o b\u1ecb suy gi\u1ea3m h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u00f3 nguy c\u01a1 cao v\u00e0 bi\u1ec3u hi\u1ec7n b\u1ec7nh r\u00f5 r\u00e0ng nh\u1ea5t. M\u00e8o con b\u1ecb l\u00e2y truy\u1ec1n t\u1eeb m\u1eb9 c\u0169ng \u1edf t\u00ecnh tr\u1ea1ng b\u1ec7nh nguy hi\u1ec3m nh\u1ea5t.<\/p>\n

Ba h\u00ecnh th\u1ee9c l\u00e2y truy\u1ec1n ch\u00ednh l\u00e0 nhi\u1ec5m tr\u00f9ng b\u1ea9m sinh, \u0103n ph\u1ea3i th\u1ecbt s\u1ed1ng b\u1ecb nhi\u1ec5m b\u1ec7nh, v\u00e0 \u0103n th\u1ef1c ph\u1ea9m ho\u1eb7c do u\u1ed1ng n\u01b0\u1edbc b\u1ecb nhi\u1ec5m nang k\u00e9n. H\u00ecnh th\u1ee9c ph\u1ee5 kh\u00e1c bao g\u1ed3m truy\u1ec1n qua s\u1eefa, truy\u1ec1n d\u1ecbch c\u01a1 th\u1ec3, v\u00e0 c\u1ea5y gh\u00e9p m\u00f4 ho\u1eb7c b\u1ed9 ph\u1eadn c\u01a1 th\u1ec3.<\/p>\n

Toxoplasmosis v\u00e0 seroreactivity T. gondii nhi\u1ec5m \u1edf th\u00fa gi\u00e0 nhi\u1ec1u h\u01a1n th\u00fa non. Ch\u00f3, m\u00e8o \u0103n th\u1ecbt s\u1ed1ng c\u00f3 nguy c\u01a1 b\u1ecb b\u1ec7nh nhi\u1ec1u h\u01a1n \u0103n th\u1ee9c \u0103n c\u00f4ng nghi\u1ec7p. Ch\u00f3 v\u00e0 m\u00e8o hoang, hay s\u1ed1ng trong t\u1ef1 nhi\u00ean c\u00f3 t\u1ef7 l\u1ec7 nhi\u1ec5m cao h\u01a1n ch\u00f3 m\u00e8o nh\u00e0. D\u1ecbch b\u1ec7nh do Toxoplasma c\u0169ng li\u00ean quan \u0111\u1ebfn c\u00e1c ngu\u1ed3n cung c\u1ea5p n\u01b0\u1edbc u\u1ed1ng v\u00e0 ngu\u1ed3n n\u01b0\u1edbc ng\u1ecdt t\u1ef1 nhi\u00ean.<\/p>\n

T. gondii c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i v\u00e0 sinh b\u00e0o t\u1eed trong n\u01b0\u1edbc bi\u1ec3n v\u00e0 t\u1ed3n t\u1ea1i \u00edt nh\u1ea5t 6 th\u00e1ng t\u1ea1i \u1edf nhi\u1ec7t \u0111\u1ed9 4\u00b0C \u0111\u1ebfn 24\u00b0C, l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y ra b\u1ec7nh t\u1eadt v\u00e0 t\u1eed vong \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa \u1edf bi\u1ec3n. \u0110\u1ed9ng v\u1eadt th\u00e2n m\u1ec1m ho\u1eb7c \u0111\u1ed9ng v\u1eadt bi\u1ec3n c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng nh\u01b0 c\u00e1c k\u00fd ch\u1ee7 trung gian.<\/p>\n

\"Toxoplasmosis-tren-cho-va-meo1\"<\/p>\n

\u00a0<\/p>\n

V\u00f2ng \u0111\u1eddi c\u1ee7a Toxoplasma gondii<\/p>\n

V\u00f2ng \u0111\u1eddi trong bi\u1ec3u m\u00f4 ru\u1ed9t: \u0111\u01b0\u1ee3c ho\u00e0n t\u1ea5t trong v\u00f2ng 3 \u0111\u1ebfn 10 ng\u00e0y sau khi m\u00e8o \u0103n nang m\u00f4 t\u1ef7 l\u1ec7 l\u00ean \u0111\u1ebfn 97% s\u1ed1 m\u00e8o. C\u00f3 hai giai \u0111o\u1ea1n sinh s\u1ea3n v\u00f4 t\u00ednh v\u00e0 sinh s\u1ea3n h\u1eefu t\u00ednh trong bi\u1ec3u m\u00f4 \u0111\u01b0\u1eddng ru\u1ed9t. Sinh s\u1ea3n v\u00f4 t\u00ednh x\u1ea3y ra khi m\u00e8o \u0103n chu\u1ed9t ch\u1ee9a m\u1ea7m b\u1ec7nh c\u00e1c bradyzoite s\u1ebd sinh s\u1ea3n v\u00f4 t\u00ednh h\u00ecnh th\u00e0nh c\u00e1c tachyzoite \u0111\u1ecbnh v\u1ecb trong c\u00e1c m\u00f4 c\u1ee7a c\u01a1 th\u1ec3. Sinh s\u1ea3n h\u1eefu t\u00ednh x\u1ea3y ra khi c\u00e1c giao t\u1eed \u0111\u1ef1c (microgamont) k\u1ebft h\u1ee3p v\u1edbi c\u00e1c giao t\u1eed c\u00e1i (macrogamont) h\u00ecnh th\u00e0nh h\u1ee3p t\u1eed (zygote) theo ph\u00e2n th\u1ea3i ra m\u00f4i tr\u01b0\u1eddng.<\/p>\n

V\u00f2ng \u0111\u1eddi ngo\u00e0i ru\u1ed9t: gi\u1ed1ng nhau \u1edf c\u00e1c k\u00fd ch\u1ee7, bao g\u1ed3m c\u1ea3 \u0111\u1ed9ng v\u1eadt g\u1eb7m nh\u1ea5m, ch\u00f3, m\u00e8o, v\u00e0 con ng\u01b0\u1eddi, kh\u00f4ng l\u1ec7 thu\u1ed9c tissue cysts (nang trong m\u00f4) ho\u1eb7c oocysts (nang k\u00e9n) \u0111\u01b0\u1ee3c \u0103n v\u00e0o.<\/p>\n

3. Sinh b\u1ec7nh h\u1ecdc<\/strong><\/p>\n

M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh ph\u1ee5 thu\u1ed9c v\u00e0o v\u1ecb tr\u00ed x\u00e2m nh\u1eadp v\u00e0 s\u1ef1 t\u1ed5n th\u01b0\u01a1ng m\u00f4. M\u1eb7c d\u00f9 nhi\u1ec5m tr\u00f9ng c\u1ea5p t\u00ednh c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong, tuy nhi\u00ean \u0111a s\u1ed1 v\u1eadt ch\u1ee7 c\u00f3 th\u1ec3 t\u1ef1 h\u1ed3i ph\u1ee5c.<\/p>\n

M\u1ed9t s\u1ed1 con ch\u00f3, m\u00e8o b\u1ecb nhi\u1ec5m toxoplasma ph\u00e1t tri\u1ec3n c\u00e1c d\u1ea5u hi\u1ec7u l\u00e2m s\u00e0ng trong khi m\u1ed9t s\u1ed1 kh\u00e1c l\u1ea1i kh\u00f4ng, c\u00f3 th\u1ec3 do m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1 nh\u01b0 tu\u1ed5i, gi\u1edbi t\u00ednh, lo\u00e0i k\u00fd ch\u1ee7, s\u1ed1 l\u01b0\u1ee3ng c\u1ee7a T. gondii, v\u00e0 giai \u0111o\u1ea1n c\u1ee7a k\u00fd sinh tr\u00f9ng. N\u00e3o, gan, ph\u1ed5i, c\u01a1 x\u01b0\u01a1ng, m\u1eaft l\u00e0 m\u1ee5c ti\u00eau ph\u1ed5 bi\u1ebfn khi T. gondii nh\u00e2n r\u1ed9ng v\u00e0 t\u1ed3n t\u1ea1i khi b\u1ec7nh chuy\u1ec3n sang m\u00e3n t\u00ednh.<\/p>\n

Stress c\u0169ng c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam t\u00ecnh tr\u1ea1ng nhi\u1ec5m tr\u00f9ng T. gondii. Khi v\u1eadt ch\u1ee7 b\u1ecb suy gi\u1ea3m mi\u1ec5n d\u1ecbch s\u1ebd nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi b\u1ec7nh kh\u00e1c v\u00ec T. gondii t\u0103ng sinh c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh c\u01a1 h\u1ed9i.<\/p>\n

Giai \u0111o\u1ea1n t\u1ed3n t\u1ea1i trong bi\u1ec3u m\u00f4 ru\u1ed9t, IgA l\u00e0m t\u0103ng ch\u1ea5t ti\u1ebft \u0111\u01b0\u1eddng ru\u1ed9t \u0111\u1ec3 T. gondii kh\u00f4ng th\u1ec3 nh\u00e2n r\u1ed9ng. Interferon (IFN)- \u03b3 v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 mi\u1ec5n d\u1ecbch d\u1ecbch th\u1ec3 r\u1ea5t quan tr\u1ecdng trong \u0111\u00e1p \u1ee9ng \u0111\u1ec1 kh\u00e1ng v\u1edbi tri\u1ec7u ch\u1ee9ng vi\u00eam n\u00e3o do Toxoplasma g\u00e2y ra.<\/p>\n

Toxoplasmosis \u1edf ch\u00f3 th\u01b0\u1eddng g\u1eafn li\u1ec1n v\u1edbi c\u00e1c nhi\u1ec5m tr\u00f9ng r\u0103ng mi\u1ec7ng. Nhi\u1ec5m tr\u00f9ng Toxoplasma nghi\u00eam tr\u1ecdng h\u01a1n \u1edf nh\u1eefng m\u00e8o \u0111\u1ed3ng nhi\u1ec5m v\u1edbi FIV, l\u00fac n\u00e0y c\u00e1c t\u1ebf b\u00e0o CD4+, CD8+, t\u1ebf b\u00e0o lympho, interleukin (IL) -2, IL-6 , IFN- \u03b3, v\u00e0 IL -12 gi\u1ea3m xu\u1ed1ng \u0111\u00e1ng k\u1ec3 c\u00f3 th\u1ec3 l\u00e0 do T.gondii \u1ee9c ch\u1ebf c\u00e1c t\u1ebf b\u00e0o TH, c\u00e1c cytokine. V\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng, m\u00e8o nhi\u1ec5m \u0111\u1ed3ng th\u1eddi FIV v\u00e0 T. gondii r\u1ea5t kh\u00f3 kh\u0103n \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3.<\/p>\n

4. Tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng<\/strong><\/p>\n

M\u00e8o con theo m\u1eb9 b\u1ecb \u1ea3nh h\u01b0\u1edfng n\u1eb7ng n\u1ec1 nh\u1ea5t do s\u1ef1 nh\u00e2n l\u00ean \u1edf to\u00e0n th\u00e2n c\u1ee7a tachyzoite. M\u00e8o con c\u00f3 bi\u1ec3u hi\u1ec7n vi\u00eam m\u00e0ng \u0111\u1ec7m v\u00f5ng m\u1ea1c m\u1eaft, h\u00f4n m\u00ea, tr\u1ea7m c\u1ea3m, h\u1ea1 th\u00e2n nhi\u1ec7t v\u00e0 ch\u1ebft \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 x\u1ea3y ra. M\u00e8o con b\u1ecb vi\u00eam n\u00e3o c\u00f3 th\u1ec3 ng\u1ee7 nhi\u1ec1u hay k\u00eau r\u00ean li\u00ean t\u1ee5c, li\u1ec7t nh\u1eb9, m\u1ea5t \u0111i\u1ec1u h\u00f2a. B\u1ee5ng to l\u00ean do gan l\u1edbn ho\u1eb7c t\u00edch d\u1ecbch xoang b\u1ee5ng.<\/p>\n

M\u00e8o tr\u01b0\u1edfng th\u00e0nh ch\u00e1n \u0103n, h\u00f4n m\u00ea, kh\u00f3 th\u1edf do vi\u00eam ph\u1ed5i l\u00e0 \u0111\u1eb7c \u0111i\u1ec3m chung c\u1ee7a b\u1ec7nh \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn. S\u1ed1t li\u00ean t\u1ee5c ho\u1eb7c kh\u00f4ng li\u00ean t\u1ee5c, s\u1ee5t c\u00e2n, v\u00e0ng da co vi\u00eam gan hay vi\u00eam \u1ed1ng m\u1eadt, vi\u00eam c\u01a1 tim, n\u00f4n m\u1eeda, ti\u00eau ch\u1ea3y, tr\u00e0n d\u1ecbch m\u00e0ng b\u1ee5ng, t\u0103ng c\u1ea3m gi\u00e1c tr\u00ean c\u01a1, ch\u00e2n \u0111i kh\u1eadp khi\u1ec5ng, vi\u00eam b\u00e0ng quan, vi\u00eam da. B\u1ec7nh c\u00f3 th\u1ec3 th\u1ebft r\u1ea5t nhanh tr\u00ean m\u1ed9t s\u1ed1 m\u00e8o c\u00f3 bi\u1ec3u hi\u1ec7n h\u00f4 h\u1ea5p v\u00e0 th\u1ea7n kinh n\u1eb7ng.<\/p>\n

Tr\u00ean ch\u00f3 con ch\u1ee7 y\u1ebfu \u1edf ch\u00f3 nh\u1ecf h\u01a1n 1 tu\u1ed5i: s\u1ed1t, vi\u00eam ami\u0111an, kh\u00f3 th\u1edf, ti\u00eau ch\u1ea3y v\u00e0 n\u00f4n m\u1eeda, v\u00e0ng da th\u01b0\u1eddng do ho\u1ea1i t\u1eed gan lan r\u1ed9ng, vi\u00eam c\u01a1 tim vi\u00eam da do \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch.<\/p>\n

Tr\u00ean ch\u00f3 tr\u01b0\u1edfng th\u00e0nh d\u1ea5u hi\u1ec7u th\u1ea7n kinh bao g\u1ed3m: t\u1ed5n th\u01b0\u01a1ng trong n\u00e3o, ti\u1ec3u n\u00e3o, ho\u1eb7c t\u1ee7y s\u1ed1ng, co gi\u1eadt, \u0111\u1ed9ng kinh, m\u1ea5t \u0111i\u1ec1u h\u00f2a, v\u00e0 li\u1ec7t ho\u1eb7c t\u00ea li\u1ec7t; d\u00e1ng \u0111i b\u1ea5t th\u01b0\u1eddng, teo c\u01a1, ho\u1eb7c c\u1ee9ng kh\u1edbp, vi\u00eam v\u00f5ng m\u1ea1c, vi\u00eam m\u00e0ng b\u1ed3 \u0111\u00e0o tr\u01b0\u1edbc, t\u0103ng s\u1ea3n bi\u1ec3u m\u00f4 l\u00f4ng mi, v\u00e0 vi\u00eam d\u00e2y th\u1ea7n kinh th\u1ea7n kinh th\u1ecb gi\u00e1c.<\/p>\n

Tr\u00ean ng\u01b0\u1eddi m\u1eafc b\u1ec7nh \u1edf m\u1ecdi l\u01b0\u1edbi tu\u1ed5i, tuy nhi\u00ean kh\u00f4ng c\u00f3 bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng n\u1ebfu c\u01a1 th\u1ec3 kh\u1ecfe m\u1ea1nh. C\u01a1 th\u1ec3 suy gi\u1ea3m mi\u1ec5n d\u1ecbch (do \u0111ang d\u00f9ng thu\u1ed1c ch\u1ed1ng ung th\u01b0 ho\u1eb7c b\u1ecb nhi\u1ec5m HIV) s\u1ebd c\u00f3 bi\u1ec3u hi\u1ec7n b\u1ec7nh bao g\u1ed3m: nhi\u1ec5m tr\u00f9ng \u1edf n\u00e3o b\u1ed9, c\u00f3 th\u1ec3 l\u00fa l\u1eabn t\u1eebng c\u01a1n, t\u00ea li\u1ec7t m\u1ed9t b\u00ean c\u01a1 th\u1ec3 ho\u1eb7c c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 ng\u00f4n ng\u1eef, vi\u00eam m\u00e0ng m\u1ea1ch \u2013 v\u00f5ng m\u1ea1c m\u1eaft.<\/p>\n

N\u1ebfu nhi\u1ec5m tr\u00f9ng x\u1ea3y ra trong 10 tu\u1ea7n \u0111\u1ea7u ti\u00ean c\u1ee7a thai k\u1ef3 \u00e0s\u1ea9y thai c\u00f3 th\u1ec3 x\u1ea3y ra ho\u1eb7c di d\u1ea1ng thai nhi, tr\u1ebb s\u01a1 sinh c\u00f3 th\u1ec3 c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 n\u00e3o, b\u1ec7nh v\u1ec1 m\u1eaft, \u0111\u1ed9ng kinh, ho\u1eb7c r\u1ed1i lo\u1ea1n v\u1ec1 m\u00e1u.<\/p>\n

5. Ch\u1ea9n \u0111o\u00e1n<\/strong><\/p>\n

Thi\u1ebfu m\u00e1u kh\u00f4ng h\u1ed3i ph\u1ee5c, s\u1ef1 gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh v\u1edbi hi\u1ec7n t\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u nghi\u00eang tr\u00e1i v\u00e0 gi\u1ea3m lympho b\u00e0o k\u00e9o d\u00e0i trong v\u00f2ng 5-12 ng\u00e0y. B\u1ea1ch c\u1ea7u t\u0103ng l\u00ean trong giai \u0111\u1ecdan h\u1ed3i ph\u1ee5c.<\/p>\n

C\u00e1c ch\u1ec9 ti\u00eau sinh h\u00f3a: protein m\u00e1u, albumin m\u00e1u gi\u1ea3m trong b\u1ec7nh c\u1ea5p t\u00ednh. Globulin m\u00e1u t\u0103ng trong b\u1ec7nh m\u00e3n t\u00ednh. ALT, AST v\u00e0 Creatine kinase t\u0103ng trong ho\u1ea1i t\u1eed gan v\u00e0 ho\u1ea1i t\u1eed c\u01a1. Bilirubin huy\u1ebft thanh t\u0103ng trong ho\u1ea1i t\u1eed gan c\u1ea5p t\u00ednh. Amylase huy\u1ebft thanh, lipase huy\u1ebft thanh, calcium huy\u1ebft thanh khi c\u00f3 vi\u00eam t\u1ee5y. C\u00f3 s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a bilirubin ni\u1ec7u v\u00e0 protein ni\u1ec7u.<\/p>\n

T\u1ebf b\u00e0o h\u1ecdc, tachyzoites c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf c\u00e1c m\u00f4 kh\u00e1c nhau v\u00e0 d\u1ecbch ch\u1ea5t c\u01a1 th\u1ec3 trong tr\u01b0\u1eddng h\u1ee3p c\u1ea5p t\u00ednh. Lympho b\u00e0o th\u01b0\u1eddng chi\u1ebfm \u01b0u th\u1ebf, v\u00e0 m\u1ed9t ph\u1ee9c h\u1ee3p c\u00e1c t\u1ebf b\u00e0o g\u00e2y ph\u1ea3n \u1ee9ng vi\u00eam \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y.<\/p>\n

Ch\u1ee5p X-quang l\u1ed3ng ng\u1ef1c m\u00e8o \u1edf th\u1ec3 c\u1ea5p t\u00ednh, c\u00f3 s\u1ef1 lan t\u1ecfa t\u1eeb m\u00f4 k\u1ebd \u0111\u1ebfn c\u00e1c ph\u1ebf nang t\u1ea1o th\u00e0nh c\u00e1c \u0111\u1ed1m tr\u00ean th\u00f9y ph\u1ed5i, tr\u00e0n d\u1ecbch m\u00e0ng ph\u1ed5i nh\u1eb9 c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n.<\/p>\n

Ki\u1ec3m tra ph\u00e2n, ch\u1ec9 1% m\u00e8o \u0111\u01b0\u1ee3c xem l\u00e0 th\u01b0\u1eddng xuy\u00ean b\u00e0i th\u1ea3i Oocysts qua ph\u00e2n m\u1eb7c d\u00f9 ki\u1ec3m tra kh\u00e1ng th\u1ec3 trong huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh.<\/p>\n

C\u00e1c test huy\u1ebft thanh tr\u00ean m\u00e8o nhi\u1ec5m T.gondii bao g\u1ed3m: Test thu\u1ed1c nhu\u1ed9m Sabin-Feldman \u0111\u1ec3 ph\u00e1t hi\u1ec7n IgG v\u00e0 IgM. Ngo\u00e0i ra, k\u0129 thu\u1eadt kh\u00e1ng th\u1ec3 h\u00f9ynh quang gi\u00e1n ti\u1ebfp (FA), Test ng\u01b0ng k\u1ebft h\u1ea1t latex (LAT) v\u00e0 phu\u01a1ng ph\u00e1p ELISA \u0111\u1ec3 ph\u00e1t hi\u1ec7n IgG.<\/p>\n

6. B\u1ec7nh t\u00edch<\/strong><\/p>\n

\u1ede m\u00e8o ho\u1ea1i t\u1eed ch\u1ee7 y\u1ebfu \u1edf gan, c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft m\u00e0ng treo ru\u1ed9t, tuy\u1ebfn t\u1ee5y, v\u00e0 ph\u1ed5i. C\u00e1c t\u1ed5n th\u01b0\u01a1ng th\u1ea7n kinh trung \u01b0\u01a1ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 t\u00ecm th\u1ea5y \u1edf ch\u00f3. U h\u1ea1t c\u00f3 th\u1ec3 c\u00f3 \u1edf ru\u1ed9t v\u00e0 c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft m\u00e0ng treo ru\u1ed9t, u nang tr\u00ean m\u00f4 \u1edf m\u00e8o b\u1ecb nhi\u1ec5m t\u1ef1 nhi\u00ean lu\u00f4n lu\u00f4n \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 Toxoplasma m\u00e0 kh\u00f4ng ph\u1ea3i Neospora. Vi\u00eam \u1ed1ng d\u1eabn m\u1eadt, \u00f4ng d\u1eabn m\u1eadt t\u0103ng s\u1ea3n, bi\u1ec3u m\u00f4 \u0111\u1ea7u \u1ed1ng m\u1eadt b\u1ecb bong tr\u00f3c v\u00e0 ti\u1ebft d\u1ecbch.<\/p>\n

\u1ede ch\u00f3 ho\u1ea1i t\u1eed chi\u1ebfm \u01b0u th\u1ebf, \u0111\u1eb7c bi\u1ec7t trong n\u00e3o, ph\u1ed5i, gan, h\u1ea1ch m\u00e0ng treo ru\u1ed9t v\u00e0 c\u00e1c n\u1ed1t b\u1ea1ch huy\u1ebft. Nhi\u1ec1u v\u1ebft lo\u00e9t \u0111\u01b0\u1eddng k\u00ednh l\u00ean \u0111\u1ebfn 10 mm trong d\u1ea1 d\u00e0y v\u00e0 ru\u1ed9t non. Th\u1ea7n kinh trung \u01b0\u01a1ng c\u00f3 v\u00f9ng b\u1ecb \u0111\u1ed5i m\u00e0u v\u00e0 ho\u1ea1i t\u1eed l\u00ean \u0111\u1ebfn 12 mm v\u00e0 teo ti\u1ec3u n\u00e3o \u0111\u00e3 \u0111\u01b0\u1ee3c quan s\u00e1t. Vi\u00eam c\u01a1 li\u00ean quan \u0111\u1ebfn c\u00e1c b\u1eafp c\u01a1 \u1edf ch\u00e2n, c\u00e1c xoang ph\u1ebf nang \u0111\u01b0\u1ee3c l\u1ea5p \u0111\u1ea7y fibrin v\u00e0 \u0111\u00f4i khi v\u1edbi t\u1ebf b\u00e0o lympho, b\u1ea1ch c\u1ea7u trung t\u00ednh, b\u1ea1ch c\u1ea7u \u00e1i toan.<\/p>\n

7. \u0110i\u1ec1u tr\u1ecb<\/strong><\/p>\n

Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb kh\u00f4ng ho\u00e0n to\u00e0n hi\u1ec7u qu\u1ea3 trong vi\u1ec7c ti\u00eau di\u1ec7t k\u00fd sinh tr\u00f9ng m\u00e0 n\u00f3 ch\u1ec9 ng\u0103n ch\u1eb7n s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a T. gondii.<\/p>\n

Clindamycin l\u00e0 thu\u1ed1c \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh toxoplasmosis l\u00e2m s\u00e0ng \u1edf ch\u00f3 v\u00e0 m\u00e8o. Clindamycin \u0111\u01b0\u1ee3c h\u1ea5p thu \u0111\u01b0\u1eddng ru\u1ed9t t\u1ed1t n\u00ean li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a thu\u1ed1c khi u\u1ed1ng v\u00e0 ti\u00eam t\u01b0\u01a1ng t\u1ef1 nhau. Tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng th\u01b0\u1eddng gi\u1ea3m b\u1edbt sau 24 \u0111\u1ebfn 48 gi\u1edd \u0111i\u1ec1u tr\u1ecb. C\u1ea3i thi\u1ec7n t\u00ednh th\u00e8m \u0103n, gi\u1ea3m s\u1ed1t.<\/p>\n

Ngo\u00e0i ra, s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a pyrimethamine v\u00e0 sulfonamides, c\u00f3 th\u1ec3 \u0111\u01b0\u01a1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb toxoplasmosis. Doxycycline v\u00e0 minocycline \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 in vitro v\u00e0 in vivo trong nhi\u1ec5m tr\u00f9ng th\u1ef1c nghi\u1ec7m \u1edf chu\u1ed9t nhi\u1ec5m toxoplasma.<\/p>\n

8. C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng b\u1ec7nh<\/strong><\/p>\n

\u2022 T\u1ed1t nh\u1ea5t n\u00ean cho m\u00e8o \u0103n th\u1ee9c \u0103n kh\u00f4 ho\u1eb7c th\u1ef1c ph\u1ea9m \u0111\u00f3ng h\u1ed9p<\/p>\n

\u2022 V\u1eadt nu\u00f4i trong nh\u00e0 kh\u00f4ng b\u00ean ti\u1ebfp x\u00fac v\u1edbi gi\u00e1n, giun \u0111\u1ea5t, v\u00e0 c\u00e1c lo\u00e0i g\u1eb7m nh\u1ea5m, \u0110V hoang d\u00e3.<\/p>\n

\u2022 N\u1ebfu b\u1ed5 sung th\u00eam th\u1ecbt n\u00ean \u0111\u01b0\u1ee3c n\u1ea5u ch\u00edn k\u1ef9, ngay c\u1ea3 khi \u0111\u00e3 \u0111\u00f4ng l\u1ea1nh tr\u01b0\u1edbc \u0111\u00f3.<\/p>\n

\u2022 M\u00e8o c\u1ea7n \u0111\u01b0\u1ee3c ng\u0103n ch\u1eb7n ti\u1ebfp x\u00fac v\u1edbi n\u01a1i ch\u1ebf bi\u1ebfn s\u1ea3n ph\u1ea9m \u0111\u1ed9ng v\u1eadt.<\/p>\n

\u2022 Vaccine ch\u1ee9a brandyzoite s\u1ed1ng nh\u01b0\u1ee3c \u0111\u1ed9c gi\u00fap l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng oocysts b\u00e0i th\u1ea3i b\u1edfi m\u00e8o t\u00e1i ph\u01a1i nhi\u1ec5m. Nh\u01b0ng lo\u1ea1i vaccine n\u00e0y hi\u1ec7n ch\u01b0a \u0111\u01b0\u1ee3c th\u01b0\u01a1ng m\u1ea1i h\u00f3a.<\/p>\n

9. C\u00e1c quan s\u00e1t s\u1ee9c kh\u1ecfe c\u1ed9ng \u0111\u1ed3ng<\/strong><\/p>\n

Tr\u00ean to\u00e0n th\u1ebf gi\u1edbi g\u1ea7n 500 tri\u1ec7u ng\u01b0\u1eddi c\u00f3 kh\u00e1ng th\u1ec3 v\u1edbi T.gondii. Ki\u1ec3m tra \u1edf M\u1ef9 c\u00f3 x\u1ea5p x\u1ec9 25-50% ng\u01b0\u1eddi c\u00f3 kh\u00e1ng th\u1ec3 v\u1edbi T.gondii, t\u1ef7 l\u1ec7 ng\u01b0\u1eddi \u1edf nh\u00f3m tu\u1ed5i t\u1eeb 12-49 l\u00e0 9% n\u0103m 1999- 2004. T\u1ea1i M\u1ef9 \u01b0\u1edbc t\u00ednh \u00edt nh\u1ea5t 50% b\u1ec7nh nhi\u1ec5m tr\u00f9ng c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng th\u1ecbt. Trong m\u1ed9t khu v\u1ef1c \u1edf mi\u1ec1n nam Chile, 57% ph\u1ee5 n\u1eef mang thai b\u1ecb nhi\u1ec5m l\u00e0 do \u0103n ph\u1ea3i th\u1ecbt, c\u00f2n l\u1ea1i l\u00e0 do nhi\u1ec5m oocysts.<\/p>\n

M\u00e8o nh\u00e0 nhi\u1ec5m b\u1ec7nh \u1edf th\u1ec3 m\u00e3n t\u00ednh v\u00e0 m\u00e8o hoang l\u00e0 ngu\u1ed3n g\u00e2y nhi\u1ec5m ch\u00ednh T.gondii \u1edf \u0111\u00f4 th\u1ecb v\u00e0 n\u00f4ng th\u00f4n. Ch\u00f3 \u0103n ph\u00e2n m\u00e8o s\u1ebd l\u00e0 vect\u01a1 v\u1eadn chuy\u1ec3n nang k\u00e9n b\u1edfi v\u00ec ch\u00fang s\u1ebd th\u1ea3i ra nang k\u00e9n trong ph\u00e2n sau 2 ng\u00e0y. S\u1ef1 truy\u1ec1n qua nhau thai \u1edf thai nhi x\u1ea3y ra th\u00f4ng qua l\u00e2y lan tachyzoite khi ph\u1ee5 n\u1eef mang thai trong th\u1eddi k\u00ec \u0111\u1ea7u. Vi\u00eam m\u00e0ng m\u1ea1ch \u2013 v\u00f5ng m\u1ea1c m\u1eaft l\u00e0 tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p nh\u1ea5t g\u00e2y ra b\u1edfi nhi\u1ec5m k\u00fd sinh tr\u00f9ng Toxoplasma \u1edf tr\u1ebb em. Nh\u1eefng tr\u1ee5c tr\u1eb7c trong trong truy\u1ec1n m\u00e1u, c\u1ea5y gh\u00e9p c\u01a1 quan c\u0169ng l\u00e0 m\u1ed9t ngu\u1ed3n l\u00e2y nhi\u1ec5m.<\/p>\n

\u0102n th\u1ecbt ch\u01b0a n\u1ea5u ch\u00edn, ho\u1eb7c th\u1ef1c ph\u1ea9m nhi\u1ec5m b\u1ea9n ch\u01b0a n\u1ea5u ch\u00edn do dao th\u1edbt, l\u00e0 nguy\u00ean nh\u00e2n ph\u1ed5 bi\u1ebfn g\u00e2y nhi\u1ec5m Toxoplasma \u1edf ng\u01b0\u1eddi. T\u1ef7 l\u1ec7 kh\u00e1ng th\u1ec3 trong huy\u1ebft thanh v\u1edbi T. gondii l\u00e0 5,2% \u1edf tr\u1ebb em s\u1ed1ng trong m\u00f4i tr\u01b0\u1eddng n\u00f4ng th\u00f4n v\u00e0 1,1% s\u1ed1ng \u1edf v\u00f9ng \u0111\u00f4 th\u1ecb. Tuy nhi\u00ean, vi\u1ec7c u\u1ed1ng s\u1eefa d\u00ea c\u0169ng c\u00f3 th\u1ec3 l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y nhi\u1ec5m b\u1ec7nh.<\/p>\n

S\u1ef1 t\u1ed3n t\u1ea1i c\u1ee7a oocysts trong m\u00f4i tr\u01b0\u1eddng c\u0169ng l\u00e0 m\u1ed9t y\u1ebfu t\u1ed1 quy\u1ebft \u0111\u1ecbnh trong vi\u1ec7c ph\u00e1t t\u00e1n v\u00e0 duy tr\u00ec c\u1ee7a b\u1ec7nh trong thi\u00ean nhi\u00ean. Oocysts c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i \u0111\u1ebfn 18 th\u00e1ng trong \u0111i\u1ec1u ki\u1ec7n m\u00f4i tr\u01b0\u1eddng .<\/p>\n

ngu\u1ed3n: vetshop<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

1. Nguy\u00ean nh\u00e2n Toxoplasma gondii l\u00e0 m\u1ed9t sinh v\u1eadt \u0111\u01a1n b\u00e0o s\u1ed1ng k\u00fd sinh n\u1ed9i b\u00e0o b\u1eaft bu\u1ed9c, l\u00e2y nhi\u1ec5m t\u1ea5t c\u1ea3 c\u00e1c \u0110V m\u00e1u n\u00f3ng k\u1ec3 c\u1ea3 con ng\u01b0\u1eddi. M\u00e8o v\u00e0 th\u00fa h\u1ecd m\u00e8o l\u00e0 v\u1eadt ch\u1ee7 ch\u00ednh b\u00e0i ti\u1ebft oocyst nang k\u00e9n. T\u1ea5t c\u1ea3 c\u00e1c k\u00fd ch\u1ee7 kh\u00f4ng thu\u1ed9c h\u1ecd m\u00e8o l\u00e0 v\u1eadt […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2301","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/2301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/comments?post=2301"}],"version-history":[{"count":0,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/2301\/revisions"}],"wp:attachment":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/media?parent=2301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/categories?post=2301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/tags?post=2301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}