{"id":2302,"date":"2018-11-19T14:28:21","date_gmt":"2018-11-19T14:28:21","guid":{"rendered":"https:\/\/robot.yeupet.vn\/benh-viem-gan-truyen-nhiem-o-cho-infectious-canine-hepatitis-ich\/"},"modified":"2018-11-19T14:28:21","modified_gmt":"2018-11-19T14:28:21","slug":"benh-viem-gan-truyen-nhiem-o-cho-infectious-canine-hepatitis-ich","status":"publish","type":"post","link":"https:\/\/robot.yeupet.vn\/index.php\/2018\/11\/19\/benh-viem-gan-truyen-nhiem-o-cho-infectious-canine-hepatitis-ich\/","title":{"rendered":"B\u1ec7nh Vi\u00eam Gan Truy\u1ec1n Nhi\u1ec5m \u1ede Ch\u00f3 \u2013 Infectious Canine Hepatitis (ICH)"},"content":{"rendered":"

1. B\u1ec7nh Vi\u00eam gan Truy\u1ec1n nhi\u1ec5m \u1edf ch\u00f3 ?<\/b><\/p>\n

L\u00e0 b\u1ec7nh l\u00e2y lan r\u1ea5t nhanh, do virus Canine Adenovirus-1 ( CAV-1 ), c\u00e1c lo\u00e0i ch\u00f3 hoang d\u00e3 v\u00e0 ch\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c ti\u00eam vaccine CVA-1 \u0111\u1ec1u c\u00f3 th\u1ec3 m\u1eafc b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t v\u1edbi ch\u00f3 d\u01b0\u1edbi m\u1ed9t n\u0103m tu\u1ed5i. B\u1ec7nh kh\u00f4ng l\u00e2y sang ng\u01b0\u1eddi.<\/span><\/p>\n

2. L\u00e2y lan ra sao ?<\/b><\/p>\n

Virus CAV-1 qua \u0111\u01b0\u1eddng mi\u1ec7ng, ti\u00eau h\u00f3a x\u00e2m nh\u1eadp m\u00f4 b\u00e0o h\u1ea7u h\u1ebft c\u00e1c c\u01a1 quan c\u01a1 th\u1ec3 c\u1ee7a ch\u00f3, d\u00f9 ch\u01b0a ph\u00e1t b\u1ec7nh ( \u1ee7 b\u1ec7nh ) nh\u01b0ng th\u1eddi gian nhi\u1ec5m CAV-1 n\u00e0y \u0111\u00e3 c\u00f3 th\u1ec3 l\u00e2y truy\u1ec1n sang ch\u00f3 kh\u00e1c qua c\u00e1c ch\u1ea5t b\u00e0i ti\u1ebft : ph\u00e2n, n\u01b0\u1edbc ti\u1ec3u v\u00e0 r\u1edbt d\u00e3i\u2026Nh\u1eefng con ch\u00f3 may m\u1eafn kh\u1ecfi b\u1ec7nh v\u1eabn mang virus t\u1edbi 9 th\u00e1ng sau.<\/p>\n

\"benh-viem-gan-truyen-nhiem-o-cho\"<\/p>\n

Canine Adenovirus d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed.<\/p>\n

3. Tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng th\u1ea5y ?<\/b><\/p>\n

Virus CAV-1 t\u1ea5n c\u00f4ng h\u1ee7y ho\u1ea1i gan, th\u1eadn v\u00e0 h\u1ec7 tu\u1ea7n ho\u00e0n r\u1ed3i nhanh ch\u00f3ng x\u00e2m nh\u1eadp to\u00e0n b\u1ed9 c\u01a1 th\u1ec3. Ch\u00f3 k\u00e9m \u0103n, b\u1ecf \u0103n r\u1ed3i chuy\u1ec3n sang h\u00f4n m\u00ea. K\u1ef3 \u1ee7 b\u1ec7nh t\u1eeb 4-7 ng\u00e0y.<\/p>\n

Th\u1ec3 qu\u00e1 c\u1ea5p t\u00ednh, ch\u00f3 \u0111\u1ed9t ng\u1ed9t b\u1ecf \u0103n, \u1ed1m x\u1ec9u, ti\u00eau ch\u1ea3y ra m\u00e1u, suy s\u1ee5p nhanh v\u00e0 t\u1eed vong ch\u1ec9 v\u00e0i gi\u1edd. Ch\u00f3 non th\u01b0\u1eddng ch\u1ebft m\u00e0 ch\u01b0a h\u1ec1 c\u00f3 tri\u1ec7u ch\u1ee9ng g\u00ec \u0111\u1eb7c bi\u1ec7t.<\/p>\n

Th\u1ec3 c\u1ea5p t\u00ednh : ch\u00f3 s\u1ed1t (39.4 \u2013 41.1oC), b\u1ecf \u0103n, ti\u00eau ch\u1ea3y v\u00e0 n\u00f4n ra m\u00e1u. Ch\u00f3 th\u01b0\u1eddng co g\u1eadp, qu\u1eb1n qu\u1ea1i do nh\u1eefng c\u01a1n \u0111au d\u1eef d\u1ed9i v\u00f9ng b\u1ee5ng do s\u01b0ng gan. \u00c1nh s\u00e1ng c\u00f3 th\u1ec3 k\u00edch th\u00edch m\u1eaft g\u00e2y \u0111au, vi\u00eam ch\u1ea3y n\u01b0\u1edbc m\u0103t r\u1ed3i c\u00f3 r\u1eed gh\u00e8n. C\u00f3 c\u00e1c \u0111i\u1ec3m n\u1ed1t xu\u1ea5t huy\u1ebft d\u01b0\u1edbi da, d\u1ec5 th\u1ea5y \u1edf v\u00f9ng da b\u1ee5ng. Ni\u00eam m\u1ea1c m\u1eaft c\u00f3 m\u00e0u v\u00e0ng r\u1ed3i to\u00e0n b\u1ed9 da v\u00e0ng nh\u01b0 ngh\u1ec7 do ch\u1ee9ng ho\u00e0ng \u0111\u1ea3n s\u1eafc t\u1ed1 m\u1eadt tr\u00e0n v\u00e0o m\u00e1u. Ch\u00f3 kh\u00f3 c\u00f3 th\u1ec3 qua kh\u1ecfi m\u1ed9t khi c\u00f3 tri\u1ec7u ch\u1ee9ng v\u00e0ng da.<\/i><\/b><\/p>\n

Kho\u1ea3ng 25% s\u1ed1 ch\u00f3 kh\u1ecfi b\u1ec7nh c\u00f3 mang di ch\u1ee9ng m\u1eaft \u201d c\u00f9i nh\u00e3n\u201d do \u0111\u1ee5c th\u1ee7y tinh th\u1ec3, c\u00f3 th\u1ec3 t\u1ef1 kh\u1ecfi sau v\u00e0i ng\u00e0y ho\u1eb7c mang di ch\u1ee9ng.<\/p>\n

\"viem-gan-truyen-nhiem-tren-cho-1\"<\/p>\n

\u00a0<\/p>\n

B\u1ec7nh th\u01b0\u1eddng gh\u00e9p v\u1edbi B\u1ec7nh Vi\u00eam kh\u00ed qu\u1ea3n-ph\u1ebf qu\u1ea3n truy\u1ec1n nhi\u1ec5m Kennel Cough k\u00e8m theo c\u00e1c tri\u1ec7u ch\u1ee9ng h\u00f4 h\u1ea5p, ho kh\u1ea1c ch\u1ea3y d\u1ecbch vi\u00eam m\u0169i, m\u1eaft\u2026<\/p>\n

4. Ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ?<\/b><\/p>\n

Qua c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng k\u1ec3 tr\u00ean, l\u00e0m test ph\u00e2n l\u1eadp virus trong ph\u00f2ng th\u00ed nghi\u1ec7m. \u1ede th\u1ec3 qu\u00e1 c\u1ea5p t\u00ednh h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f3 c\u01a1 h\u1ed9i ch\u1eefa tr\u1ecb, ch\u00f3 ch\u1ebft trong v\u00f2ng v\u00e0i gi\u1edd \u0111\u1ebfn 2- 3 ng\u00e0y sau \u0111\u1ecf b\u1ec7nh.<\/p>\n

Kh\u00f4ng c\u00f3 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u. Ch\u1ee7 y\u1ebfu \u0111i\u1ec1u tr\u1ecb theo tri\u1ec7u ch\u1ee9ng: b\u00f9 n\u01b0\u1edbc, c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i, truy\u1ec1n d\u1ecbch \u0111\u01b0\u1eddng glucose, lactated Ringer v\u00e0 c\u00e1c lo\u1ea1i kh\u00e1ng sinh ch\u1ed1ng vi\u00eam nhi\u1ec5m k\u1ebf ph\u00e1t, vitamine, t\u0103ng ch\u1ee9c n\u0103ng gan th\u1eadn, v\u00e0 ch\u0103m s\u00f3c theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a c\u00e1c b\u00e1c s\u1ef9 th\u00fa y.<\/p>\n

5. Ph\u00f2ng b\u1ec7nh v\u00e0 Ki\u1ec3m d\u1ecbch ra sao?<\/b><\/p>\n

Ch\u00f3 ph\u1ea3i \u0111\u01b0\u1ee3c ti\u00eam ph\u00f2ng vaccine ph\u00f2ng b\u1ec7nh Vi\u00eam gan truy\u1ec1n nhi\u1ec5m l\u00e0 lo\u1ea1i vaccine nh\u01b0\u1ee3c \u0111\u1ed9c c\u00f3 ch\u1ee9a h\u1ed1n h\u1ee3p virus CAV-1 v\u00e0 CVA-2, ph\u00f2ng c\u1ea3 b\u1ec7nh Vi\u00eam kh\u00ed qu\u1ea3n- ph\u1ebf qu\u1ea3n truy\u1ec1n nhi\u1ec5m Kennel Cough. K\u00fd t\u1ef1 \u201cH\u201d tr\u00ean c\u00e1c nh\u00e3n vaccine l\u00e0 ch\u1eef \u0111\u1ea7u c\u1ee7a\u201d Hepatitis \u0111\u1ec3 m\u1ecdi ng\u01b0\u1eddi nh\u1eadn bi\u1ebft d\u1ec5 d\u00e0ng.<\/p>\n

Ch\u00f3 non ph\u1ea3i \u0111\u01b0\u1ee3c ti\u00eam vaccine ngay t\u1eeb 6-8 tu\u1ea7n tu\u1ed5i r\u1ed3i nh\u1eafc l\u1ea1i l\u00fac 12 tu\u1ea7n tu\u1ed5i. H\u1eb1ng n\u0103m nh\u1eafc l\u1ea1i m\u1ed9t l\u1ea7n.<\/p>\n

Ch\u00f3 \u1ed1m ho\u1eb7c nghi \u1ed1m b\u1ec7nh, ph\u1ea3i c\u00e1ch ly v\u00e0 ki\u1ec3m so\u00e1t v\u1ec7 s\u1ecbnh, ti\u00eau \u0111\u1ed9c ch\u1eb7t ch\u1ebd. \u0110\u1eb7c bi\u1ec7t x\u1eed l\u00fd ch\u1ea5t b\u00e0i ti\u1ebft, n\u01b0\u1edbc r\u1eeda chu\u1ed3ng, khu v\u1ef1c nu\u00f4i ch\u00f3.<\/p>\n

C\u00e1ch ly theo d\u00f5i ch\u00f3 m\u1edbi nh\u1eadp v\u1ec1, ch\u00f3 mua ph\u1ea3i c\u00f3 b\u1ea3o \u0111\u1ea3m d\u00e3 ti\u00eam ph\u00f2ng vaccine \u0111\u1ea7y \u0111\u1ee7 theo quy tr\u00ecnh. Kh\u00f4ng t\u1eadp trung nh\u1eefng con ch\u00f3 ch\u01b0a ti\u00eam ph\u00f2ng d\u1ecbch trong c\u00e1c Dog show, Festival, Petshop, ph\u1ea3i c\u00f3 khu \u0111i\u1ec1u tr\u1ecb b\u1ec7nh truy\u1ec1n nhi\u1ec5m ri\u00eang v\u01a1i \u0111\u1ee7 \u0111i\u1ec1u ki\u1ec7n s\u00e1t tr\u00f9ng, v\u1ec7 sinh.<\/p>\n

_______________________________________________________________________________________<\/p>\n

B\u00e0i Vi\u1ebft sau \u0111\u00e2y k\u1ef9 l\u01b0\u1ee1ng h\u01a1n d\u00e0nh cho c\u00e1c b\u1ea1n c\u00f3 chuy\u00ean m\u00f4n<\/strong>
\n1.) C\u0103n nguy\u00ean g\u00e2y b\u1ec7nh<\/strong><\/p>\n

L\u00e0 b\u1ec7nh l\u00e2y lan r\u1ea5t nhanh, do virus Canine Adenovirus-1 ( CAV-1 ), c\u00e1c lo\u00e0i ch\u00f3 hoang d\u00e3 v\u00e0 ch\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c ti\u00eam vaccine CVA-1 \u0111\u1ec1u c\u00f3 th\u1ec3 m\u1eafc b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t v\u1edbi ch\u00f3 d\u01b0\u1edbi m\u1ed9t n\u0103m tu\u1ed5i. B\u1ec7nh kh\u00f4ng l\u00e2y sang ng\u01b0\u1eddi.
\nB\u1ec7nh vi\u00eam gan truy\u1ec1n nhi\u1ec5m tr\u00ean ch\u00f3 g\u00e2y ra b\u1edfi canine adenovirus (CAV-1) c\u00f3 huy\u1ebft thanh \u0111\u1ed3ng nh\u1ea5t tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, t\u01b0\u01a1ng \u0111\u1ed3ng mi\u1ec5n d\u1ecbch v\u1edbi adenovirus tr\u00ean ng\u01b0\u1eddi. CAV-1 c\u00f3 kh\u00e1ng nguy\u00ean kh\u00e1c bi\u1ec7t so v\u1edbi CAV-2 (lo\u1ea1i \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t vaccin cho b\u1ec7nh h\u00f4 h\u1ea5p tr\u00ean ch\u00f3). Kh\u00e1ng nguy\u00ean c\u1ee7a CAV-2 \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp t\u1eeb ru\u1ed9t ch\u00f3 con b\u1ecb ti\u00eau ch\u1ea3y xu\u1ea5t huy\u1ebft, t\u1eeb nh\u1eefng ch\u00f3 b\u1ecb ho c\u0169i ch\u00f3 (Kennel’s disease) v\u1edbi d\u1ea5u hi\u1ec7u ti\u00eau ch\u1ea3y. Gi\u1ed1ng nh\u01b0 c\u00e1c adenovirus kh\u00e1c, CAV-1 c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ec1 kh\u00e1ng trong m\u00f4i tr\u01b0\u1eddng b\u1ea5t ho\u1ea1t, kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t cao v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c kh\u1eed tr\u00f9ng v\u00e0 m\u1ed9t s\u1ed1 lo\u1ea1i h\u00f3a ch\u1ea5t, \u1ed5n \u0111\u1ecbnh khi ti\u1ebfp x\u00fac v\u1edbi m\u1ed9t t\u1ea7n s\u1ed1 nh\u1ea5t \u0111\u1ecbnh c\u1ee7a b\u1ee9c x\u1ea1 c\u1ef1c t\u00edm.<\/p>\n

2.) Sinh b\u1ec7nh h\u1ecdc (ph\u01b0\u01a1ng th\u1ee9c l\u00e2y lan)<\/strong><\/p>\n

Sau khi ti\u1ebfp x\u00fac mi\u1ec7ng-m\u0169i virus \u0111\u1ecbnh v\u1ecb t\u1ea1i h\u1ea1ch amidan, sau \u0111\u00f3 n\u00f3 l\u00e2y lan \u0111\u1ebfn c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft v\u00e0 h\u1ec7 b\u1ea1ch huy\u1ebft tr\u01b0\u1edbc khi v\u00e0o m\u00e1u th\u00f4ng qua c\u00e1c \u1ed1ng l\u1ed3ng ng\u1ef1c. Nhi\u1ec5m tr\u00f9ng huy\u1ebft k\u00e9o d\u00e0i 4-8 ng\u00e0y sau khi nhi\u1ec5m, sau \u0111\u00f3 virus x\u00e2m nhi\u1ec5m nhanh ch\u00f3ng v\u00e0o c\u00e1c m\u00f4 v\u00e0 c\u00f3 m\u1eb7t trong ch\u1ea5t ti\u1ebft c\u1ee7a c\u01a1 th\u1ec3, bao g\u1ed3m n\u01b0\u1edbc b\u1ecdt, n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n. T\u1ebf b\u00e0o nhu m\u00f4 gan, t\u1ebf b\u00e0o n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u c\u1ee7a nhi\u1ec1u m\u00f4 bao g\u1ed3m h\u1ec7 th\u1ed1ng th\u1ea7n kinh trung \u01b0\u01a1ng l\u00e0 nh\u1eefng v\u1ecb tr\u00ed virus \u0111\u1ecbnh v\u1ecb v\u00e0 g\u00e2y nhi\u1ec5m tr\u00f9ng v\u00e0 c\u00e1c b\u1ec7nh t\u00edch tr\u00ean c\u00e1c c\u01a1 quan n\u00e0y.
\nC\u00e1c bi\u1ebfn ch\u1ee9ng th\u01b0\u1eddng li\u00ean quan \u0111\u1ebfn sinh b\u1ec7nh h\u1ecdc c\u1ee7a ICH, nh\u1eefng ch\u00f3 suy nh\u01b0\u1ee3c d\u1ec5 d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng vi\u00eam b\u1ec3 th\u1eadn do virus t\u1ea5n c\u00f4ng. Ch\u1ea3y m\u00e1u n\u1ed9i m\u00f4 (Disseminated intravascular coagulation \u2013 DIC) l\u00e0 m\u1ed9t bi\u1ebfn ch\u1ee9ng th\u01b0\u1eddng xuy\u00ean c\u1ee7a ICH v\u00e0 c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u1ed5n th\u01b0\u01a1ng tr\u00ean t\u1ebf b\u00e0o n\u1ed9i m\u00f4, d\u1eabn \u0111\u1ebfn ho\u1ea1t h\u00f3a c\u00e1c c\u01a1 ch\u1ebf \u0111\u00f4ng m\u00e1u, ho\u1eb7c gan k\u00e9m ch\u1ee9c n\u0103ng d\u1eabn \u0111\u1ebfn gi\u1ea3m t\u1ed5ng h\u1ee3p c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u \u1edf gan.<\/p>\n

\"viem-gan-truyen-nhiem-tren-cho\"<\/p>\n

Canine Adenovirus d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed.<\/em><\/p>\n

3.) K\u1ebft qu\u1ea3 l\u00e2m s\u00e0ng<\/strong><\/p>\n

ICH l\u00e0 th\u01b0\u1eddng th\u1ea5y nh\u1ea5t tr\u00ean nh\u1eefng ch\u00f3 nh\u1ecf d\u01b0\u1edbi 1 m\u1ed9t n\u0103m tu\u1ed5i, m\u1eb7c d\u00f9 ch\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c ti\u00eam ch\u1ee7ng \u1edf m\u1ecdi l\u1ee9a tu\u1ed5i c\u0169ng c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng. Ch\u00f3 b\u1ecb \u1ea3nh h\u01b0\u1edfng nghi\u00eam tr\u1ecdng s\u1ebd h\u1ea5p h\u1ed1i v\u00e0 ch\u1ebft trong v\u00e0i gi\u1edd sau khi xu\u1ea5t hi\u1ec7n c\u00e1c d\u1ea5u hi\u1ec7u l\u00e2m s\u00e0ng.
\nD\u1ea5u hi\u1ec7u l\u00e2m s\u00e0ng \u1edf giai \u0111o\u1ea1n \u0111\u1ea7u c\u1ee7a nhi\u1ec5m tr\u00f9ng bao g\u1ed3m: t\u0103ng nhi\u1ec7t \u0111\u1ed9 tr\u1ef1c tr\u00e0ng (39,4\u00b0C \u0111\u1ebfn 41,1\u00b0C), t\u0103ng t\u1ea7n s\u1ed1 h\u00f4 h\u1ea5p. S\u1ed1t c\u00f3 th\u1ec3 kh\u00f4ng c\u00f2n, s\u01b0ng h\u1ea1ch amidan th\u01b0\u1eddng k\u1ebft h\u1ee3p v\u1edbi vi\u00eam h\u1ecdng v\u00e0 vi\u00eam thanh qu\u1ea3n, ho v\u00e0 c\u00f3 \u00e2m khan tr\u00ean \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p. Th\u01b0\u1eddng th\u1ea5y c\u00e1c n\u1ed1t b\u1ea1ch huy\u1ebft tr\u00ean c\u1ed5 l\u1edbn l\u00ean g\u00e2y ph\u00f9 n\u1ec1 d\u01b0\u1edbi da \u0111\u1ea7u v\u00e0 c\u1ed5. \u0110au b\u1ee5ng v\u00e0 gan th\u01b0\u1eddng r\u00f5 r\u00e0ng trong c\u00e1c ca b\u1ec7nh c\u1ea5p, \u0111\u1ed1m xu\u1ea5t huy\u1ebft v\u00e0 c\u00e1c v\u1ebft b\u1ea7m lan r\u1ed9ng d\u01b0\u1edbi da, ch\u1ea3y m\u00e1u cam v\u00e0 ch\u1ea3y m\u00e1u t\u0129nh m\u1ea1ch c\u0169ng th\u01b0\u1eddng x\u1ea3y ra. V\u00e0ng da kh\u00f4ng ph\u1ed5 bi\u1ebfn trong gia \u0111o\u1ea1n c\u1ea5p c\u1ee7a ICH, nh\u01b0ng n\u00f3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong m\u1ed9t s\u1ed1 ch\u00f3 s\u1ed1ng s\u00f3t qua giai \u0111o\u1ea1n ph\u00e1t c\u1ea5p t\u00ednh c\u1ee7a b\u1ec7nh. Tr\u01b0\u1edbng b\u1ee5ng do s\u1ef1 t\u00edch t\u1ee5 c\u1ee7a ch\u1ea5t l\u1ecfng (Bao g\u1ed3m huy\u1ebft thanh v\u00e0 m\u00e1u) ho\u1eb7c do xu\u1ea5t huy\u1ebft n\u1ed9i. D\u1ea5u hi\u1ec7u th\u1ea7n kinh trung \u01b0\u01a1ng bao g\u1ed3m: \u1ee7 r\u0169, m\u1ea5t ph\u01b0\u01a1ng h\u01b0\u1edbng, co gi\u1eadt, h\u00f4n m\u00ea ho\u1eb7c h\u00f4n m\u00ea s\u00e2u trong giai \u0111o\u1ea1n cu\u1ed1i c\u1ee7a b\u1ec7nh. Ch\u00f3 b\u1ecb \u1ea3nh h\u01b0\u1edfng nh\u1eb9 c\u00f3 th\u1ec3 ph\u1ee5c h\u1ed3i sau khi h\u1ebft s\u1ed1t, tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng c\u00e1c bi\u1ebfn ch\u1ee9ng c\u1ee7a ICH th\u01b0\u1eddng xuy\u00ean k\u00e9o d\u00e0i 5-7 ng\u00e0y tr\u01b0\u1edbc khi gi\u1ea3m b\u1edbt. Ph\u00f9 gi\u00e1c m\u1ea1c v\u00e0 vi\u00eam m\u00e0ng gi\u1eefa c\u1ee7a m\u1eaft th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n khi c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng m\u1ea5t d\u1ea7n.<\/p>\n

4.) Ch\u1ea9n \u0111o\u00e1n<\/strong><\/p>\n

Ch\u1ea9n \u0111o\u00e1n huy\u1ebft thanh h\u1ecdc s\u1edbm \u0111\u1ed1i v\u1edbi ICH bao g\u1ed3m gi\u1ea3m b\u1ea1ch c\u1ea7u lymph\u00f4 v\u00e0 b\u1ea1ch c\u1ea7u trung t\u00ednh, t\u0103ng b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 lympho b\u00e0o x\u1ea3y ra sau khi ch\u00f3 h\u1ed3i ph\u1ee5c h\u1ed3i c\u00e1c bi\u1ebfn ch\u1ee9ng c\u1ee7a b\u1ec7nh. Protein huy\u1ebft thanh thay \u0111\u1ed5i v\u1edbi \u03b12\u00ac-globulin gia t\u0103ng t\u1ea1m th\u1eddi v\u00e0 \u03b3-globulin t\u0103ng ch\u1eadm v\u00e0o ng\u00e0y th\u1ee9 7 sau khi ti\u00eam ph\u00f2ng, \u0111\u1ea1t \u0111\u1ec9nh \u0111i\u1ec3m v\u00e0o ng\u00e0y th\u1ee9 21.<\/p>\n

\"viem-gan-truyen-nhiem-tren-cho\"<\/p>\n

T\u0103ng m\u1ee9c \u0111\u1ed9 alanine aminotransferase (ALT), aspartate aminotransferase v\u00e0 alkaline phosphatase v\u00e0 alkaline phosphatase ph\u1ee5 thu\u1ed9c v\u00e0o th\u1eddi \u0111i\u1ec3m l\u1ea5y m\u1eabu v\u00e0 m\u1ee9c \u0111\u1ed9 ho\u1ea1i t\u1eed gan. C\u00e1c enzyme n\u00e0y ti\u1ebfp t\u1ee5c t\u0103ng cho \u0111\u1ebfn ng\u00e0y th\u1ee9 14 sau khi ti\u00eam ph\u00f2ng, sau \u0111\u00f3 gi\u1ea3m d\u1ea7n, m\u1eb7c d\u00f9 n\u1ed3ng \u0111\u1ed9 n\u00e0y c\u00f3 th\u1ec3 t\u0103ng \u0111\u1ec1u \u0111\u1eb7n l\u1ea1i (nh\u1eadn th\u1ea5y tr\u00ean nh\u1eefng ch\u00f3 b\u1ecb vi\u00eam gan m\u00e3n). S\u1ef1 gia t\u0103ng ALT (c\u00f3 t\u1ea7m quan tr\u1ecdng c\u1ee7a ch\u1ea9n \u0111o\u00e1n, nh\u1eb1m \u0111o l\u01b0\u1eddng m\u1ee9c \u0111\u1ed9 ho\u1ea1i t\u1eed gan) th\u01b0\u1eddng kh\u00f4ng t\u01b0\u01a1ng x\u1ee9ng so v\u1edbi s\u1ef1 gia t\u0103ng bilirubin huy\u1ebft thanh, S\u1ef1 ch\u00eanh l\u1ec7ch n\u00e0y l\u00e0 \u0111i\u1ec3n h\u00ecnh cho ICH v\u00e0 kh\u00e1c bi\u1ec7t v\u1edbi h\u1ea7u h\u1ebft c\u00e1c nguy\u00ean nh\u00e2n kh\u00e1c g\u00e2y ho\u1ea1i t\u1eed gan lan r\u1ed9ng (quanh c\u00e1c ti\u1ec3u m\u1ea1ch m\u00e1u c\u1ee7a ti\u1ec3u th\u00f9y). H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y tr\u00ean nh\u1eefng ch\u00f3 trong giai \u0111o\u1ea1n cu\u1ed1i c\u1ee7a c\u0103n b\u1ec7nh n\u00e0y.
\n\u0110\u1eb7c t\u00ednh \u0111\u00f4ng m\u00e1u b\u1ea5t th\u01b0\u1eddng c\u1ee7a DIC \u0111\u1ec5 d\u00e0ng nh\u1eadn th\u1ea5y \u1edf pha nhi\u1ec5m tr\u00f9ng huy\u1ebft c\u1ee7a b\u1ec7nh. Gi\u1ea3m ti\u1ec3u c\u1ea7u.
\nProtein (ch\u1ee7 y\u1ebfu l\u00e0 albumin ni\u1ec7u) \u0111\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng th\u1eadn g\u00e2y ra b\u1edfi virus v\u00e0 th\u01b0\u1eddng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n tr\u00ean ph\u00e2n t\u00edch ng\u1eabu nhi\u00ean n\u01b0\u1edbc ti\u1ec3u, b\u1edfi v\u00ec n\u1ed3ng \u0111\u1ed9 l\u1edbn h\u01a1n 50mg\/dL. S\u1ef1 t\u0103ng t\u00ednh th\u1ea5m \u1edf c\u1ea7u th\u1eadn c\u00f3 th\u1ec3 do virus \u0111\u1ecbnh v\u1ecb t\u1ea1i \u0111\u00f3, trong giai \u0111o\u1ea1n \u0111\u1ea7u c\u1ee7a nhi\u1ec5m tr\u00f9ng.
\nTh\u1ea3o lu\u1eadn k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m cho th\u1ea5y ch\u1ea9n \u0111o\u00e1n l\u00e2m s\u00e0ng \u0111\u1ed1i v\u1edbi ICH l\u00e0 ph\u01b0\u01a1ng ti\u1ec7n ch\u00ednh. Tr\u01b0\u1edbc khi ch\u1ebft (kh\u00f4ng c\u1ea7n thi\u1ebft cho \u0111i\u1ec1u tr\u1ecb), c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m huy\u1ebft thanh, ph\u00e2n l\u1eadp virus b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p mi\u1ec5n d\u1ecbch hu\u1ef3nh quang, nhu\u1ed9m virus t\u1ea1i c\u00e1c m\u1eabu m\u00f4 b\u1ec7nh. Ki\u1ec3m tra huy\u1ebft thanh bao g\u1ed3m ph\u1ea3n \u1ee9ng trung h\u00f2a virus, ng\u01b0ng k\u1ebft h\u1ed3ng c\u1ea7u gi\u00e1n ti\u1ebfp, k\u1ebft h\u1ee3p b\u1ed5 th\u1ec3, ph\u1ea3n \u1ee9ng kh\u00e1ng nguy\u00ean kh\u00e1ng th\u1ec3 v\u00e0 ELISA. C\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y th\u01b0\u1eddng cho th\u1ea5y n\u1ed3ng \u0111\u1ed9 kh\u00e1ng th\u1ec3 cao h\u01a1n sau khi b\u1ecb nhi\u1ec5m virus \u0111\u1ed9c l\u1ef1c cao t\u01b0\u01a1ng ph\u1ea3n v\u1edbi vaccin MLV.
\nCAV-1 c\u00f3 th\u1ec3 d\u1ec5 d\u00e0ng ph\u00e2n l\u1eadp v\u00ec n\u00f3 \u0111\u1ec1 kh\u00e1ng cao trong m\u1ed9i tr\u01b0\u1eddng v\u00e0 d\u1ec5 d\u00e0ng nh\u00e2n l\u00ean trong m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y t\u1ebf b\u00e0o c\u1ee7a m\u1ed9t s\u1ed1 lo\u00e0i, bao g\u1ed3m c\u1ea3 ch\u00f3. B\u1ec7nh t\u00edch t\u1ebf b\u00e0o \u0111i\u1ec3n h\u00ecnh c\u1ee7a adenovirus bao g\u1ed3m k\u1ebft t\u1ee5 v\u00e0 ly gi\u1ea3i t\u1ebf b\u00e0o m\u1ed9t l\u1edbp. Khi hi\u1ec7n t\u01b0\u1ee3ng nhi\u1ec5m tr\u00f9ng huy\u1ebft b\u1eaft \u0111\u1ea7u (v\u00e0o ng\u00e0y th\u1ee9 5 PI), CAV-1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y t\u1eeb b\u1ea5t k\u1ef3 m\u00f4 c\u01a1 th\u1ec3 ho\u1eb7c ho\u1eb7c ch\u1ea5t ti\u1ebft. Nu\u00f4i c\u1ea5y virus t\u1eeb gan ch\u00f3 th\u01b0\u1eddng r\u1ea5t kh\u00f3, b\u1edfi v\u00ec arginase c\u1ee7a gan \u1ee9c ch\u1ebf virus sao ch\u00e9p nucleotide, virus kh\u00f4ng th\u1ec3 ph\u00e2n l\u1eadp t\u1eeb gan qu\u00e1 10 ng\u00e0y PI, ngay c\u1ea3 tr\u00ean nh\u1eefng ch\u00f3 b\u1ecb vi\u00eam gan m\u00e3n, c\u00f3 l\u1ebd b\u1edfi v\u00ec \u0111\u1ed9 tr\u1ec5 c\u1ee7a virus. Th\u1eadn l\u00e0 c\u01a1 quan virus khu tr\u00fa v\u00e0 CAV-1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp t\u1eeb n\u01b0\u1edbc ti\u1ec3u \u00edt nh\u1ea5t 6-9 th\u00e1ng sau khi nhi\u1ec5m b\u1ec7nh \u0111\u1ea7u ti\u00ean.<\/p>\n

5.) B\u1ec7nh l\u00fd<\/strong><\/p>\n

Kh\u00e1m t\u1eed, ki\u1ec3m tra sinh thi\u1ebft m\u00f4 t\u1eeb nh\u1eefng ch\u00f3 b\u1ec7nh c\u00f3 th\u1ec3 ch\u1ea9n \u0111o\u00e1n ICH. Ch\u00f3 ch\u1ebft trong giai \u0111o\u1ea1n c\u1ea5p t\u00ednh c\u1ee7a b\u1ec7nh th\u01b0\u1eddng th\u00e2n th\u1ecbt c\u00f2n t\u1ed1t, ph\u00f9 v\u00e0 xu\u1ea5t huy\u1ebft c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft tr\u00ean b\u1ec1 m\u1eb7t v\u00e0 m\u00f4 d\u01b0\u1edbi da c\u1ed5. Xoang b\u1ee5ng c\u00f3 th\u1ec3 ch\u1ee9a ch\u1ea5t l\u1ecfng m\u00e0u s\u1eafc thay \u0111\u1ed5i t\u1eeb trong \u0111\u1ebfn \u0111\u1ecf t\u01b0\u01a1i, xu\u1ea5t huy\u1ebft v\u00e0 t\u1ee5 huy\u1ebft tr\u00ean t\u1ea5t c\u1ea3 b\u1ec1 m\u1eb7t m\u00e0ng thanh d\u1ecbch. Gan s\u01b0ng to, s\u1eadm m\u00e0u, v\u1ebft l\u1ed1m \u0111\u1ed1m tr\u00ean b\u1ec1 m\u1eb7t v\u00e0 c\u00f3 d\u1ecbch, fibrin th\u01b0\u1eddng hi\u1ec7n di\u1ec7n tr\u00ean b\u1ec1 m\u1eb7t gan v\u00e0 trong c\u00e1c v\u1ebft n\u1ee9t gian th\u00f9y. \u0110i\u1ec3n h\u00ecnh l\u00e0 t\u00fai m\u1eadt d\u1ea7y v\u00e0 ph\u00f9 n\u1ec1 v\u00e0 c\u00f3 m\u00e0u \u0111\u1ee5c m\u1edd m\u00e0u xanh-tr\u1eafng. Fibrin c\u00f3 th\u1ec3 l\u1eafng \u0111\u1ecdng tr\u00ean b\u1ec1 m\u1eb7t m\u00e0ng thanh d\u1ecbch xoang b\u1ee5ng. Xu\u1ea5t huy\u1ebft \u1ed1ng ti\u00eau h\u00f3a , l\u00e1ch s\u01b0ng v\u00e0 ph\u00ecnh ra tr\u00ean b\u1ec1 m\u1eb7t c\u1eaft.
\nICH g\u00e2y b\u1ec7nh t\u00edch tr\u00ean c\u00e1c c\u01a1 quan kh\u00e1c nh\u01b0: xu\u1ea5t huy\u1ebft v\u00e0 nh\u1ed3i huy\u1ebft tr\u00ean v\u1ecf th\u1eadn, c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft ph\u1ebf qu\u1ea3n xu\u1ea5t huy\u1ebft v\u00e0 ph\u00f9 n\u1ec1. Xu\u1ea5t huy\u1ebft r\u1ea3i r\u00e1c tr\u00ean n\u00e3o \u1edf ph\u1ea7n n\u00e3o gi\u1eefa v\u00e0 \u0111u\u00f4i cu\u1ed1ng n\u00e3o. T\u1ed5n th\u01b0\u01a1ng tr\u00ean m\u1eaft \u0111\u01b0\u1ee3c \u0111\u1eb7c tr\u01b0ng b\u1edfi \u0111\u1ee5c gi\u00e1c m\u1ea1c v\u00e0 g\u00e2y t\u00edch d\u1ecbch.
\nThay \u0111\u1ed5i m\u00f4 b\u1ec7nh h\u1ecdc trong gan c\u1ee7a nh\u1eefng ch\u00f3 ch\u1ebft v\u00ec b\u1ec7nh vi\u00eam gan c\u1ea5p t\u00ednh bao g\u1ed3m ho\u1ea1i t\u1eed lan r\u1ed9ng kh\u1eafp ti\u1ec3u th\u00f9y gan. Tr\u00ean nh\u1eefng ch\u00f3 ho\u1ea1i t\u1eed gan nh\u1eb9, m\u1ee9c \u0111\u1ed9 ho\u1ea1i t\u1eed c\u00e1c m\u00f4 gan \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh trong c\u00e1c ti\u1ec3u th\u00f9y gan (h\u00ecnh 4-4).
\nThay \u0111\u1ed5i m\u00f4 h\u1ecdc tr\u00ean di\u1ec7n r\u1ed9ng x\u1ea3y ra \u1edf c\u00e1c c\u01a1 quan kh\u00e1c l\u00e0 k\u1ebft qu\u1ea3 c\u1ee7a ch\u1ea5n th\u01b0\u01a1ng n\u1ed9i m\u1ea1c g\u00e2y ra b\u1edfi virus. Th\u1ec3 v\u00f9i ban \u0111\u1ea7u \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong c\u00e1c ti\u1ec3u c\u1ea7u th\u1eadn nh\u01b0ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong n\u1ed9i m\u1ea1c m\u1ea1ch m\u00e1u h\u00ecnh \u1ed1ng c\u1ee7a th\u1eadn, c\u00f3 s\u1ef1 t\u1eadp trung c\u1ee7a b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 c\u00e1c t\u1ebf b\u00e0o \u0111\u01a1n nh\u00e2n trong v\u00f9ng v\u1ecf v\u00e0 t\u1ee7y th\u1eadn, nh\u1eefng thay \u0111\u1ed5i nh\u1eb9 th\u01b0\u1eddng ti\u1ebfn tri\u1ec3n \u0111\u1ebfn x\u01a1 h\u00f3a m\u00f4 k\u1ebd. C\u01a1 quan lympho bao g\u1ed3m c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft, amidan v\u00e0 l\u00e1ch b\u1ecb xung huy\u1ebft v\u1edbi s\u1ef1 x\u00e2m nh\u1eadp c\u1ee7a b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 t\u1ebf b\u00e0o \u0111\u01a1n nh\u00e2n, c\u00e1c nang b\u1ea1ch huy\u1ebft ph\u00e2n t\u00e1n quanh v\u00f9ng ho\u1ea1i t\u1eed. th\u1ec3 v\u00f9i trong nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong c\u00e1c t\u1ebf b\u00e0o n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u v\u00e0 c\u00e1c m\u00f4 b\u00e0o, c\u00e1c v\u00e1ch ng\u0103n ph\u1ebf nang v\u00e0 quanh ph\u1ebf qu\u1ea3n ph\u1ed5i d\u00e0y l\u00ean v\u1edbi s\u1ef1 t\u00edch l\u0169y c\u00e1c lympho, Ph\u1ebf nang ch\u1ee9a \u0111\u1ea7y d\u1ecbch ti\u1ebft bao g\u1ed3m h\u1ed3ng c\u1ea7u, fibrin v\u00e0 ch\u1ea5t l\u1ecfng.
\nThay \u0111\u1ed5i tr\u00ean m\u1eaft \u0111\u01b0\u1ee3c \u0111\u1eb7c tr\u01b0ng b\u1edfi vi\u00eam m\u1ed1ng m\u1eaft v\u00e0 c\u01a1 m\u00ed m\u1eaft c\u00f3 u h\u1ea1t v\u1edbi s\u1ef1 gi\u00e1n \u0111o\u1ea1n n\u1ed9i m\u00f4 gi\u00e1c m\u1ea1c, gi\u00e1c m\u1ea1c ph\u00f9 n\u1ec1. M\u1ed1ng v\u00e0 m\u00ed m\u1eaft b\u1ecb ngh\u1ebdn v\u1edbi c\u00e1c t\u1ebf b\u00e0o vi\u00eam.<\/p>\n

\"viem-gan-truyen-nhiem-tren-cho1\"<\/p>\n

Th\u1ec3 v\u00f9i \u0111\u01b0\u1ee3c th\u1ea5y trong ICH \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e2n lo\u1ea1i nh\u01b0 Cowdry type A v\u00e0 c\u1ea3 m\u00f4 ngo\u1ea1i b\u00ec v\u00e0 m\u00f4 mesodermal (ch\u00fang c\u00f3 nhi\u1ec1u \u1edf gan), \u0111i\u1ec1u n\u00e0y l\u00e0m cho ch\u00fang tr\u1edf th\u00e0nh m\u00f4 h\u1ee3p l\u00fd cho xem k\u00ednh, ch\u00fang thu \u0111\u01b0\u1ee3c b\u1eb1ng sinh thi\u1ebft ho\u1eb7c kh\u00e1m t\u1eed (H\u00ecnh 4-5). Ban \u0111\u1ea7u ph\u00ec \u0111\u1ea1i nh\u00e2n c\u00e1c t\u1ebf b\u00e0o theo sau l\u00e0 h\u1ec7 th\u1ed1ng nhi\u1ec5m s\u1eafc \u0111\u1ecdng l\u1ea1i ph\u1ea7n r\u00eca (t\u1ea1o th\u00e0nh trung t\u00e2m), h\u1ea1t nh\u00e2n c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c bao quanh b\u1edfi m\u1ed9t v\u1ea7ng s\u00e1ng c\u1ee7a nhi\u1ec5m s\u1eafc th\u1ec3. C\u00e1c th\u1ec3 v\u00f9i ban \u0111\u1ea7u l\u00e0 \u01b0a acid nh\u01b0ng tr\u1edf n\u00ean \u01b0a ki\u1ec1m nh\u01b0 b\u00e1m r\u00eca nhi\u1ec5m s\u1eafc th\u1ec3. C\u1ea7n ch\u00fa \u00fd th\u1ec3 v\u00f9i trong t\u1ebf b\u00e0o gan do ICH v\u00e0 do c\u00e1c b\u1ec7nh virus kh\u00e1c.<\/p>\n

6.) \u0110i\u1ec1u tr\u1ecb<\/strong><\/p>\n

Theo d\u00f5i s\u1ef1 ti\u1ebfn tri\u1ec3n c\u1ee7a tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng. \u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 cho \u0111\u1ebfn khi c\u00e1c t\u1ebf b\u00e0o gan h\u1ed3i ph\u1ee5c. Th\u00f4ng \u1ed1ng t\u0129nh m\u1ea1ch (catheter) ngay l\u1eadp t\u1ee9c \u0111\u1ed1i v\u1edbi ch\u00f3 b\u1ecb \u1ea3nh h\u01b0\u1edfng nghi\u00eam tr\u1ecdng v\u1edbi b\u1ec7nh. Li\u1ec7u ph\u00e1p truy\u1ec1n d\u1ecbch v\u1edbi dung d\u1ecbch Lactate Ringer\u2019s s\u1ebd b\u00f9 ch\u1ea5t \u0111i\u1ec7n gi\u1ea3i do n\u00f4n m\u1eeda, ti\u00eau ch\u1ea3y v\u00e0 h\u1ed7 tr\u1ee3 trong vi\u1ec7c l\u00e0m gi\u1ea3m nhi\u1ec7t \u0111\u1ed9 c\u01a1 th\u1ec3. Tr\u00ean nh\u1eefng ch\u00f3 qu\u00e1 suy nh\u01b0\u1ee3c ph\u1ea3i \u0111\u01b0\u1ee3c duy tr\u00ec l\u01b0\u1ee3ng ch\u1ea5t l\u1ecfng h\u1eb1ng ng\u00e0y (45 ml\/kg) b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam.
\nH\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft g\u00e2y ra t\u00ecnh tr\u1ea1ng h\u00f4n m\u00ea, do \u0111\u00f3 ti\u00eam t\u0129nh m\u1ea1ch glucose 50% (0,5 ml\/kg) n\u00ean \u0111\u01b0\u1ee3c \u0111\u01b0a ra trong kho\u1ea3ng th\u1eddi gian 5 ph\u00fat\/l\u1ea7n. H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft c\u00f3 th\u1ec3 s\u1ebd t\u00e1i di\u1ec5n n\u1ebfu kh\u00f4ng duy tr\u00ec truy\u1ec1n li\u00ean t\u1ee5c glucose \u01b0u tr\u01b0\u01a1ng, truy\u1ec1n glucose \u01b0u tr\u01b0\u01a1ng n\u00ean \u0111\u01b0\u1ee3c ti\u1ebfp t\u1ee5c v\u1edbi t\u1ed1c \u0111\u1ed9 kh\u00f4ng l\u1edbn h\u01a1n 0,5-0,9gr\/kg \/gi\u1edd m\u1edbi th\u1ea5y hi\u1ec7u qu\u1ea3. \u0110i\u1ec1u tr\u1ecb \u0111\u1ec3 gi\u1ea3m n\u1ed3ng \u0111\u1ed9 amoniac trong m\u00e1u h\u01b0\u1edbng v\u00e0o vi\u1ec7c gi\u1ea3m d\u1ecb h\u00f3a protein c\u1ee7a vi khu\u1ea9n ru\u1ed9t gi\u00e0 v\u00e0 t\u00e1i h\u1ea5p thu amoniac trong \u1ed1ng th\u1eadn, s\u1ea3n xu\u1ea5t amoniac t\u1eeb s\u1ef1 tho\u00e1i h\u00f3a protein trong ru\u1ed9t c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3m b\u1eb1ng c\u00e1ch gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng protein v\u00e0 ng\u0103n ch\u1eb7n xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a. Ru\u1ed9t gi\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ee5t r\u1eeda b\u1eb1ng c\u00e1ch l\u00e0m s\u1ea1ch v\u00e0 axit h\u00f3a nh\u1eb1m l\u00e0m gi\u1ea3m \u1ee9 ru\u1ed9t v\u00e0 l\u00e0m ch\u1eadm s\u1ef1 h\u1ea5p th\u1ee5 amoniac. Qu\u00e1 tr\u00ecnh axit h\u00f3a ru\u1ed9t c\u0169ng c\u00f3 th\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch cho \u0103n, u\u1ed1ng lactulose \u0111\u1ed1i v\u1edbi nh\u1eefng ch\u00f3 kh\u00f4ng \u00f3i m\u1eeda. T\u00e1i h\u1ea5p thu amoniac \u1edf th\u1eadn c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3m b\u1eb1ng c\u00e1ch d\u00f9ng thu\u1ed1c kali h\u00f3a (b\u1eb1ng mi\u1ec7ng) v\u00e0 c\u00e2n b\u1eb1ng chuy\u1ec3n h\u00f3a ki\u1ec1m. Axit h\u00f3a n\u01b0\u1edbc ti\u1ec3u v\u1edbi acid ascorbic (m\u1ed9t acid ho\u00e1 kh\u00f4ng \u0111\u1ed9c h\u1ea1i) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 amoniac t\u00e1i h\u1ea5p thu qua th\u1eadn.<\/p>\n

7.) Ph\u00f2ng ch\u1ed1ng<\/strong><\/p>\n

Mi\u1ec5n d\u1ecbch m\u1eb9 truy\u1ec1n
\nTh\u1eddi gian mi\u1ec5n d\u1ecbch th\u1ee5 \u0111\u1ed9ng nh\u1eadn \u0111\u01b0\u1ee3c trong ch\u00f3 con ph\u1ee5 thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9 kh\u00e1ng th\u1ec3 c\u1ee7a ch\u00f3 m\u1eb9. Ti\u00eam ch\u1ee7ng ICH th\u01b0\u1eddng th\u00e0nh c\u00f4ng khi kh\u00e1ng th\u1ec3 m\u1eb9 truy\u1ec1n (maternally derived antibody \u2013 MDA) c\u00f3 n\u1ed3ng \u0111\u1ed9 gi\u1ea3m xu\u1ed1ng d\u01b0\u1edbi 100 (c\u00f3 th\u1ec3 x\u1ea3y ra b\u1eaft \u0111\u1ea7u t\u1eeb 5-7 tu\u1ea7n tu\u1ed5i). M\u1ee9c \u0111\u1ed9 ICH MDAs trong ch\u00f3 con m\u1edbi sinh gi\u1ea3m kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u1edbi n\u1ed3ng \u0111\u1ed9 14 \u0111\u1ebfn 16 tu\u1ea7n.
\nTi\u00eam ph\u00f2ng
\nVaccin MLV CAV-1 \u0111\u00e3 \u0111\u01b0\u1ee3c ng\u01b0ng trong h\u1ea7u h\u1ebft c\u00e1c n\u01b0\u1edbc tr\u00ean th\u1ebf gi\u1edbi \u0111\u1ec3 kh\u00e1ng nguy\u00ean MLV CAV-2 c\u00f3 m\u1eb7t trong h\u1ea7u nh\u01b0 t\u1ea5t c\u1ea3 c\u00e1c th\u1ecb tr\u01b0\u1eddng vaccin.
\nTi\u00eam vaccin CAV-2, lo\u1ea1i \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nh\u01b0 l\u00e0 m\u1ed9t s\u1ef1 thay th\u1ebf trong c\u00f4ng t\u00e1c ph\u00f2ng ch\u1ed1ng ICH. Vaccin CAV-2 bi\u1ebfn \u0111\u1ed5i hi\u1ebfm khi g\u00e2y b\u1ec7nh \u1edf m\u1eaft ho\u1eb7c th\u1eadn khi s\u1eed d\u1ee5ng c\u00e1c con \u0111\u01b0\u1eddng kh\u00e1c nhau (ti\u00eam b\u1eafp, ti\u00eam d\u01b0\u1edbi da, ho\u1eb7c m\u0169i), m\u1eb7c d\u00f9 virus c\u00f3 th\u1ec3 khu tr\u00fa v\u00e0 b\u00e0i th\u1ea3y qua \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean. Khi th\u1ef1c nghi\u1ec7m ti\u00eam v\u00e0o l\u1edbp gi\u1eefa nh\u00e3n c\u1ea7u, virus vaccin t\u0103ng sinh v\u00e0 g\u00e2y t\u1ed5n th\u01b0\u01a1ng m\u1eaft t\u01b0\u01a1ng t\u1ef1 nh\u01b0 khi ch\u1ee7ng CAV-1. Khi \u0111\u01b0\u1ee3c ho\u1eb7c ti\u00eam t\u0129nh m\u1ea1ch ho\u1eb7c x\u00f4ng qua \u0111\u01b0\u1eddng m\u0169i, vaccine CAV-2 MLV c\u00f3 th\u1ec3 g\u00e2y b\u1ec7nh h\u00f4 h\u1ea5p nh\u1eb9 v\u1edbi ho v\u00e0 s\u01b0ng h\u1ea1ch amidan, m\u1eb7c d\u00f9 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng v\u00e0 t\u1ef1 h\u1ed3i ph\u1ee5c. Tuy nhi\u00ean, \u0111\u1ec3 ph\u00f2ng ng\u1eeba chung, th\u1ef1c hi\u1ec7n cung c\u1ea5p vaccin c\u1ea9n th\u1eadn \u0111\u1ec3 tr\u00e1nh v\u00f4 t\u00ecnh g\u00e2y kh\u00ed dung vaccin ti\u00eam trong khi s\u1eed d\u1ee5ng.
\nCh\u01b0\u01a1ng tr\u00ecnh vaccin \u0111\u1ec1 ngh\u1ecb \u0111\u1ec3 b\u1ea3o v\u1ec7 ch\u1ed1ng l\u1ea1i ICH bao g\u1ed3m \u00edt nh\u1ea5t hai li\u1ec1u (ch\u00f3 tr\u00ean 3 \u0111\u1ebfn 4 tu\u1ea7n) t\u1ea1i 8 \u0111\u1ebfn 10 v\u00e0 12 \u0111\u1ebfn 14 tu\u1ea7n tu\u1ed5i. \u0110i\u1ec1u n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u00f4ng qua s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a kh\u00e1ng nguy\u00ean virus ICH v\u1edbi canine distemper virus v\u00e0 parvovirus. Ti\u00eam ch\u1ee7ng th\u01b0\u1eddng xuy\u00ean h\u01a1n trong c\u00e1c khu v\u1ef1c c\u00f3 t\u1ef7 l\u1ec7 nhi\u1ec5m cao. \u0110\u1ed1i v\u1edbi li\u1ec1u nh\u1eafc l\u1ea1i, vaccin MLV c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ti\u00eam m\u1ed7i 3 n\u0103m\/l\u1ea7n nh\u01b0 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh b\u1edfi c\u00e1c nghi\u00ean c\u1ee9u. Ti\u00eam ch\u1ee7ng h\u00e0ng n\u0103m (nh\u01b0 vi\u1ec7c th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc \u0111\u00e2y) l\u00e0 kh\u00f4ng c\u1ea7n thi\u1ebft v\u00ec qu\u00e1 tr\u00ecnh b\u1ea3o v\u1ec7 l\u00e2u d\u00e0i c\u1ee7a vaccin MLV.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

1. B\u1ec7nh Vi\u00eam gan Truy\u1ec1n nhi\u1ec5m \u1edf ch\u00f3 ? L\u00e0 b\u1ec7nh l\u00e2y lan r\u1ea5t nhanh, do virus Canine Adenovirus-1 ( CAV-1 ), c\u00e1c lo\u00e0i ch\u00f3 hoang d\u00e3 v\u00e0 ch\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c ti\u00eam vaccine CVA-1 \u0111\u1ec1u c\u00f3 th\u1ec3 m\u1eafc b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t v\u1edbi ch\u00f3 d\u01b0\u1edbi m\u1ed9t n\u0103m tu\u1ed5i. B\u1ec7nh kh\u00f4ng l\u00e2y sang ng\u01b0\u1eddi. 2. L\u00e2y lan […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2302","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/2302","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/comments?post=2302"}],"version-history":[{"count":0,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/posts\/2302\/revisions"}],"wp:attachment":[{"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/media?parent=2302"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/categories?post=2302"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/robot.yeupet.vn\/index.php\/wp-json\/wp\/v2\/tags?post=2302"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}